Hydrophobically modified biomineralized polysaccharide alginate membrane for sustained smart drug delivery

Self-assembled nanoparticles of acetylated cashew gum: Characterization and evaluation as potential drug carrier

“…The release profile observed is not due to the dialyze membrane effect as a control experiment shows that 84% indomethacin released in 2 h (data show in supplementary file). According to the literature, hydrophobized alginate with IND loading as high as 75.6% presented a release of circa 60% within 12 h, and the authors noted that the insertion of hydrophobic groups into the alginate decreased the drug release (Shi et al, 2012). In another study, hydrophobized amylopectin presented lower released values of 20.0-46.0% IND over 8 h (Lu et al, 2011).…”

“…Hydrophobized or hydrophobic polymers can self-assemble in aqueous solution forming nanoparticles. In this context, amphiphilic block copolymers and hydrophobized polymers have been previously synthesized and their structure-function relationships studied (Ding et al, 2011;Lee et al, 2012;Na et al, 2003;Suksiriworapong, Sripha, & Heinze, 2008;Lucero, Claro, Casas, & Jimenez-Castellanos, 2013), dextran (Hassani et al, 2012;Aumelas, Serrero, Durand, Dellacherie, & Leonard, 2007;Hornig, Bunjes, & Heinze, 2009;Nichifor, Lopes, Carpov, & Melo, 1999), pullulan (Lee et al, 2012;Zhang et al, 2009), chondroitin sulfate (Park et al, 2010), chitosan (Hassani et al, 2012;Hwang, Kim, Kwon, & Kim, 2008), hyaluronic acid (Surace et al, 2009), amylose (Lalush, Bar, Zakaria, Eichler, & Shimoni, 2005), heparin (Park et al, 2004) and curdlan (Na, Park, Kim, & Bae, 2000), amylopectin (Lu, Zhang, Wang, & Chen, 2011) alginate (Shi, Zhang, Qi, & Cao, 2012;Pawar & Edgar, 2012) have been used for the formation of self-assembling nanoparticles with a view to their application as drug carriers.…”

Mineralization of hydroxyapatite upon a unique xanthan gum hydrogel by an alternate soaking process

“…Anionic polysaccharides such as alginate, hyaluronic acid, and chondroitin sulfate are potential optimal templates for the mineralization of Hap because their anionic surface can bind Ca 2+ ions and can control crystal nucleation and growth by lowering the interfacial energy between the crystal and the surface (Arias & Fernandez, 2008). Therefore, various Hap-composited materials have been prepared by using anionic polysaccharides for biomedical applications, including bone tissue engineering (Chen, Ushida & Tateishi, 2002;Du, Song, Cui, Yang & Li, 2011;Green et al, 2005;Shi, Zhang, Qi & Cao, 2012;Shi, Zhang, Yang & Tang, 2009;Zhong & Chu, 2012).…”

Toward the Next Generation of Sustainable Membranes from Green Chemistry Principles

“…Alginate is nontoxic and has suitable biocompatibility, 102 with potential applications in the biomedical field for cell growth, drug delivery, and tissue engineering. 103 Alginate has been increasingly employed in membrane fabrication processes in the last two decades. Its unique structure helps absorption of water, dyes, and heavy metals, 104 and alginate-based materials can be applied in pervaporation dehydration, water treatment, oil−water separation, and organic solvent nanofiltration.…”

“…It can combine with Na + or Ca 2+ and produce sodium alginate (NaAlg) or calcium alginate (CaAlg). Alginate is nontoxic and has suitable biocompatibility, with potential applications in the biomedical field for cell growth, drug delivery, and tissue engineering …”