Hydrothermal Synthesis of Si‐doped Hydroxyapatite Nanopowders: Mechanical and Bioactivity Evaluation

Abstract

Si‐doped hydroxyapatite nanoparticles (n‐SixHA) were prepared by hydrothermal synthesis from calcium nitrate tetrahydrate and diammonium hydrogen orthophosphate. A rod‐like morphology was obtained for all the powders irrespective of the incorporated Si‐doping level. But the crystallinity of the n‐SixHA powders, the density achieved upon sintering powder compacts and their mechanical properties (three‐point‐bending strength), as well as their biomineralization activity evaluated by immersing them into simulated body fluid (SBF) were found to be dependent on the Si‐doping amount.

Synthesis, characterization, in vitro bioactivity and antimicrobial activity of magnesium and nickel doped silicate hydroxyapatite

“…(4a)) [39]. The presence of oxygen ions results in the distortion of the hexagonal symmetry of HA, which results in the formation of energetically unstable material that decomposes into β-TCP during the calcination process [40]. The use of lower calcination temperature and absence β-TCP as a secondary phase in XRD patterns confirmed that the mechanism proposed in Eq.…”