Hydroxyapatite-Coated Femoral Stem Survivorship at 10 Years

Lee, Gregory Y.; Srivastava, Ajay Kumar; D'Lima, Darryl D.; Pulido, Pam; Colwell, Clifford W.

doi:10.4028/0-87849-961-x.1069

Cited by 4 publications

(5 citation statements)

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“…However, our results are comparable with the mid‐term outcomes of THA using cementless components. Lee et al evaluated 96 patients (103 hips) who had received the same stem as in our study and reported 100% stem survivorship at mean follow‐up of 10 years (range: 7–12 years). Cortical hypertrophy, radiolucent lines, and osteolysis were reported in 41%, 21%, and 9% of the stems, respectively.…”

Section: Discussionmentioning

confidence: 71%

Effect of bone type on clinical and radiographic outcomes of a proximally-coated cementless stem in primary total hip arthroplasties

et al. 2014

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ABSTRACT:We determined the effect of pre-operative bone structure upon the temporal effects of remodeling after total hip arthroplasty (THA) in a series of uncemented implants. We evaluated 345 patients (375 hips), who had either Dorr Type-A (238 hips) or Type-B (137 hips) bone, and who received a proximally-coated cementless THA and were followed for a mean of 6 years. Outcomes evaluated included aseptic survivorship, Harris hip scores, and radiographic evaluation for patterns of remodeling. The aseptic survivorship (97.5% vs. 98%) and the mean final Harris hip scores (92 vs. 94 points) were similar between Types-A and -B bone, respectively. Bone remodeling was seen significantly earlier and over a longer duration for patients who had Type-B bone. At 5-years, periprosthetic condensation (78% vs. 54%) and cortical hypertrophy (53% vs. 37%) were significantly higher and radiolucencies at any zone were lower (53% vs. 37%) in Type-B compared to Type-A bone. There was increased condensation in men and higher cortical hypertrophy in women. Various radiographic remodeling differences may not negatively impact clinical outcome at mid-term follow-up.Morphologic bone type appears to be predictive of physiologic response to loading. ß

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Section: Discussionmentioning

confidence: 71%

Effect of bone type on clinical and radiographic outcomes of a proximally-coated cementless stem in primary total hip arthroplasties

et al. 2014

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“…Very high survival rates are reported [5,[9][10][11][12][13][14][15][16] for HA-coated femoral stems in total hip replacement (THR) arthroplasty, usually superior to those for cemented or uncoated cementless stems. Good load transfer between the stem and the attached bone has been observed, with little stress shielding [9,11,[16][17][18][19].…”

Section: Introductionmentioning

confidence: 99%

Suspension thermal spraying of hydroxyapatite: Microstructure and in vitro behaviour

Bolelli

Bellucci

Cannillo

et al. 2014

Materials Science and Engineering: C

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“…This is because the crystalline phase in this material can transform into an amorphous calcium phosphate, as discussed elsewhere, 18 which exhibits an excellent bioreactivity equivalent to that of amorphous Bioglass 1 . A number of clinical studies 33,34 on the bioactivity of calcium phosphates with different crystallinities have also revealed that after initial slight differences there was no significant disadvantage of highly crystalline hydroxyapatite several months after implantation.…”

Section: Effects Of Crystallization and Surface-functionalisation On mentioning

confidence: 99%

Bioglass®‐derived glass–ceramic scaffolds: Study of cell proliferation and scaffold degradation in vitro

Chen

Efthymiou

Salih

et al. 2007

J Biomedical Materials Res

121

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Cell support function as well as cell proliferation on highly porous Bioglass(R)-derived glass-ceramic scaffolds (designed for bone tissue engineering) have been assessed in vitro using osteoblast-like cells (MG 63) cultured for up to 6 days. The biodegradation and mechanical stability of the scaffolds in the cell-culture medium have also been investigated. It was found that the scaffolds had excellent cell supporting ability, with cells effectively infiltrating into and surviving at the center of the scaffolds. A quantitative study using the AlamarBlue assay revealed that the proliferation of cells on the glass-ceramic materials was comparable to that on the noncrystallized Bioglass. While the crystalline phase in the glass-ceramic scaffolds transformed into a biodegradable amorphous calcium phosphate phase during cell culture, the mechanical strength of the scaffolds was maintained when compared with that of scaffolds incubated in simulated body fluid or immersed in cell-free culture medium. It is believed that the attached cells and collagen secreted by cells could fill the micropores and microcracks on the surface of the foam struts, thus contributing to the mechanical stability of the degrading scaffolds. In summary, the developed glass-ceramic scaffolds possess the most essential features of a scaffold for bone tissue engineering: they are capable to support and foster relevant cells, able to provide temporary mechanical function, and biodegradable.

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Hydroxyapatite-Coated Femoral Stem Survivorship at 10 Years

Cited by 4 publications

References 0 publications

Effect of bone type on clinical and radiographic outcomes of a proximally-coated cementless stem in primary total hip arthroplasties

Effect of bone type on clinical and radiographic outcomes of a proximally-coated cementless stem in primary total hip arthroplasties

Suspension thermal spraying of hydroxyapatite: Microstructure and in vitro behaviour

Bioglass®‐derived glass–ceramic scaffolds: Study of cell proliferation and scaffold degradation in vitro

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