Hydroxychloroquine as a treatment for atrophoderma of Pasini and Pierini

Carter, John D.; Valeriano, Joanne; Vasey, Frank B.

doi:10.1111/j.1365-4632.2006.03021.x

Cited by 21 publications

(13 citation statements)

References 6 publications

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“…[6] Carter et al suggested that hydroxychloroquine is a therapeutic option for chronic refractory APP. [11] In one case, the Q-switched alexandrite laser was effective in decreasing hyperpigmentation, but it did not help with atrophy. [12] …”

Section: Discussionmentioning

confidence: 98%

Two uncommon cases of idiopathic atrophoderma of pasini and pierini: Multiple and giant

Zhang¹,

Zhu²

2011

Indian J Dermatol Venereol Leprol

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We report a 39-year-old Chinese man presenting with approximately 200 atrophic brownish patches for 10 years, whose clinical manifestation and pathological features were consistent with the findings of idiopathic atrophoderma of Pasini and Pierini. Another described case was a 62-year-old woman who had a gradually increasing asymptomatic hyperpigmented and depressed patch on her right lumbosacral region over a period of 7 years. At the time of consultation, the size of the lesion was approximately 27 x 23 cm.

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Section: Discussionmentioning

confidence: 98%

Two uncommon cases of idiopathic atrophoderma of pasini and pierini: Multiple and giant

Zhang¹,

Zhu²

2011

Indian J Dermatol Venereol Leprol

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“…Laboratory evaluations were within normal range and histological examination revealed a characteristic decrease of dermal thickness. The course of the disease is usually benign, but the poor response to conventional therapy is considered a problem for both the patient and the physician (10,14). Skin changes that persist and remain the same size over time nonetheless sometimes develop further and increase in both number and size for 10 to 20 years without a significant improvement despite treatment.…”

Section: Discussionmentioning

confidence: 99%

Atrophoderma of Pasini and Pierini in a young adult: a case report

Gerqari

Ferizi

Gerqari

2019

Acta Dermatovenerologica Alpina Pannonica Et Adriatica

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Atrophoderma of Pasini and Pierini is a skin atrophy presenting as single or multiple sharply demarcated, hyperpigmented, non-indurated patches, with a slight depression of the skin, that can converge and form a confluent area with atrophy as a consequence. The condition was first described by Pasini in 1923 and subsequently by Pierini in 1936. They distinguished this form of atrophy from other diseases and conditions in which the atrophy is morphologically and clinically different. The disease was initially associated with Borrelia burgdorferi infection; however, at present, various theories have emerged for the appearance of the disease, linked to genetic, neurogenetic, and immunological factors. Here we present a patient that was admitted to the hospital due to disseminated lesions on the skin of the lower limbs, with slightly pigmented and atrophic skin along with irregular borders varying in size, from several mm to a few cm, clearly demarcated from the healthy skin, with no history of a tick bite or a family history of similar skin disorders.

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“…Topical calcineurin inhibitors were found to have variable responses. 16 Q-switched alexandrite laser has also resulted in some clinical improvement of hyperpigmented lesions. 17 The differential diagnosis includes Linear Atrophoderma of Moulin (LAM) and morphea, where distinctions need to be made to provide a diagnosis to the patient ( Table 2).…”

Section: Discussionmentioning

confidence: 99%