Bioclimatic comfort, anthropogenic load, conditions and nature of the labor process, lifestyle are among the main factors of the environment and professional activities of people. Purpose - to assess the incidence of persons of an organized team in the ecological and hygienic conditions of the city of Krasnoyarsk. Object - prevalence, primary incidence for the period 2016-2021. The state of anthropogenic pollution of the city territory was judged according to official sources. Assessed the working conditions and the nature of the labor process. The chemical load defines Krasnoyarsk as one of the leaders in the total morbidity of the region and as a risk area in the region in terms of morbidity exceeding the average. Uncomfortable living environment is noted for 9-10 months. The work of the observation group according to the degree of harmfulness and danger - class 3.3. In the structure of work, 80% of the time is mental [intellectual loads (3.2), emotional loads (3.2), work schedule (3.2)], physical activities, periodic long business trips with high emotional and physical stress. In the lifestyle of eating disorders, drinking alcohol, smoking. The prevalence of diseases was 1.6 times higher than in the adult population of Krasnoyarsk and (or) the region: a significant excess of 1.35-4.8 times in 6 classes and lower values of 1.2 times in 2 classes of diseases. In the primary morbidity, the leading pathologies were respiratory, genitourinary, musculoskeletal, trauma and poisoning (including the consequences of external causes), hearing aid, the share of which in the structure reached 80.3%. With the exception of the pathology of the hearing aid, it reflected the incidence of the adult population of the Krasnoyarsk Territory, as well as the dynamics of long-term morbidity. The peculiarities of morbidity in a cohort of an organized team are determined by their initial state of health, conditions of professional activity and lifestyle. The need to assess the health risk of the influence of synergistic factors of habitability of the population is actualized, taking into account the characteristics of professional activity and lifestyle.