Introduction. Analysis and generalization of the results of scientific research of the institutions of the Federal Service for Supervision in Protection of the Rights of Consumer and Man Wellbeing (Rospotrebnadzor)institutions of a hygienic profile are extremely important in the scientific substantiation of ensuring sanitary and epidemiological well-being and managing risks to the health of the Russian population. The purpose of the study is to analyze the results, achievements and prospects of the scientific substantiation of ensuring sanitary and epidemiological well-being and managing risks to the health of the population of the Russian Federation. Materials and methods. An expert-analytical study was carried out. The analysis materials are the main results of the activities of scientific institutions of the Rospotrebnadzor of the hygienic profile in the implementation of the industry research program of Rospotrebnadzor for 2021-2025. “Scientific substantiation of the national system for ensuring sanitary and epidemiological well-being, managing health risks and improving the quality of life of the population of Russia”, as well as of the Federal Program (FP) “Clean Air” of the National Project (NP) “Ecology”, FP “Clean Water” NP “Housing and Urban Environment”, FP “Strengthening Public Health” NP “Demography”, the State Program “Provision of chemical and biological safety of the Russian Federation for the period 2021-2024”, the Federal Target Program “Ensuring nuclear and radiation safety for 2016-2020 and for the period up to 2030”. Results. Within the framework of the industry program, in the first year of its implementation, six SanPiNs, 668 hygienic standards were approved, 20 analytical reviews were prepared. 23 patents for inventions, 45 - for industrial designs, 34 - certificates for computer programs, 178 objects of intellectual activity were registered. Based on the materials of scientific research, 95 articles were published in the journals Web of Science, 328 - Scopus, 802 - RSCI. 40 monographs, books and manuals have been published. 11 PhD, 2 doctoral dissertations were defended. Limitations. The research materials are limited to the results of scientific research of the Research Institute of Hygienic Profile of Rospotrebnadzor, obtained in 2021. Conclusion. The results of the activities of the NIO Rospotrebnadzor in 2021 indicate that the set of tasks assigned to them to ensure the sanitary and epidemiological well-being of the population is being successfully implemented. Further development of interagency cooperation is required (with scientific institutions of the Russian Academy of Sciences, the Ministry of Education and Science of Russia, other ministries and departments, with medical universities); interaction with problem committees of the Scientific Council of Rospotrebnadzor, as well as further modernization and renovation of the park of laboratory and medical equipment of scientific organizations.
