Hypertension and Related Cardiovascular Disease Burden in China

Bundy, Joshua D; He, Jiang

doi:10.1016/j.aogh.2016.02.002

Cited by 123 publications

(96 citation statements)

References 33 publications

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“…It is considered one of the major risk factors for the development of cardiovascular diseases such as stroke, ischemic heart disease, and heart failure. [1–4] Despite the recent advances in the development of antihypertensive therapeutic treatments and in the pathophysiology of hypertension, the prevalence of hypertension in China remains considerably high, whereas the rates of blood pressure (BP) control are notably low. The outline of the Report on Cardiovascular Disease in China (2014) demonstrated that the hypertension control (BP <140/90 mm Hg) rate was approximately 9.3% of all patients, and/or 27.4% of treated patients, although 42.6% of hypertensive patients in China were aware of their condition and 34.1% were receiving treatment.…”

Section: Introductionmentioning

confidence: 99%

Nonspecific ST-T changes associated with unsatisfactory blood pressure control among adults with hypertension in China

et al. 2017

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Nonspecific ST-segment and T-wave (ST-T) changes represent one of the most prevalent electrocardiographic abnormalities in hypertensive patients. However, a limited number of studies have investigated the association between nonspecific ST-T changes and unsatisfactory blood pressure (BP) control in adults with hypertension.The study population comprised 15,038 hypertensive patients, who were selected from 20,702 participants in the China Stroke Primary Prevention Trial. The subjects were examined with electrocardiogram test at the initial visit in order to monitor baseline heart activity. According to the results of the electrocardiogram (defined by Minnesota coding), the subjects were divided into 2 groups: ST-T abnormal and ST-T normal. Unsatisfactory BP control was defined as systolic BP ≥140 mm Hg or diastolic BP ≥90 mm Hg following antihypertensive treatment during the 4.5-year follow-up period. Multivariate analysis was used to analyze the association between nonspecific ST-T abnormalities and unsatisfactory BP control.Nonspecific ST-T changes were common in hypertensive adults (approximately 8.5% in the study), and more prevalent in women (10.3%) and diabetic patients (13.9%). The unsatisfactory BP control rate was high in the total population (47.0%), notably in the ST-T abnormal group (55.5%). The nonspecific ST-T abnormal group exhibited a significantly greater rate of unsatisfactory BP control (odds ratio [OR] 1.20, 95% confidence interval [CI] [1.06, 1.36], P = 0.005]), independent of traditional risk factors, as demonstrated by multivariate regression analysis. Notable differences were further observed in male subjects (OR 1.51, 95% CI [1.17, 1.94], P = 0.002) and in patients with comorbid diabetes (OR 1.47, 95% CI [1.04, 2.07], P = 0.029).Greater rates of unsatisfactory BP control in hypertensive patients with electrocardiographic nonspecific ST-T abnormalities were observed, notably in the subcategories of the male subjects and the diabetic patients.

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Section: Introductionmentioning

confidence: 99%

Nonspecific ST-T changes associated with unsatisfactory blood pressure control among adults with hypertension in China

et al. 2017

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“…Genotypes and alleles are expressed as number (percentage). * Represents the p<0.05.†P values was calculated using χ2 test of 3×2 contingency table for the genotype distribution and 2×2 contingency table for allele distribution. OR , 95% CI and p were calculated using logistic regression analysis (backward LR) with (§) and without (‡) adjusting for work sites, age, length of work, current smokers, current drinkers, BMI , FBG , TC , TG , HDL-C and LDL-C .…”

Section: Resultsmentioning

confidence: 99%

“…All other subjects without hypertension or other infections were defined as control group. Body weight and height were measured, and body mass index (BMI) was defined as the weight in kilograms divided by the height in metres squared (weight/height2). …”

Section: Methodsmentioning

confidence: 99%

“…Essential hypertension affects 20%–30% of the population worldwide and contributes significantly to cardiovascular mortality and morbidity 3. In China, the prevalence of hypertension has been rapidly escalating recently, and blood pressure (BP)-related cardiovascular diseases is recognised as a leading cause of mortality among Chinese adults 2. Hypertension is a complex trait resulting from the interactions of multiple genetic, epigenetic and environmental interfering factors 1.…”

Section: Introductionmentioning

confidence: 99%

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Interaction of heat shock protein 70 (HSP70) polymorphisms and occupational hazards increases the risk of hypertension in coke oven workers

Zheng

Lyu

et al. 2018

Occup Environ Med

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“…The prevalence of hypertension and high blood pressure are also increasing with its rapid development. A study showed that 33.6% (35.3% in men and 32% in women) or 335.8 million (178.6 million men and 157.2 million women) of the Chinese adult population had hypertension in 2010 [38]. Since China is major country for most of the production of materials and part required by all over the world, we see a lot of large scale industries and factories, few of the studies done in different cities of China are given below for a brief acknowledgement of occupational noise and prevalence of hypertension in China.…”

Section: Noise and Hypertensionmentioning

confidence: 99%

Occupational Noise Exposure in Relation to Hypertension: A Cross-sectional Study in the Steel Factory

Shrestha¹,

Mai²

2017

Occup Med Health Aff

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Background: Noise has been acknowledged as one of the most prevailing physical hazard in occupational health and safety. Noise can possess both permanent and temporary health outcomes. The hazardous exposure to occupational noise is generally identified to have aural effects. However in past few years, researches have been carried out to perceive the association between noise exposure and cardiovascular diseases. Yet, the topic has been under controversies regarding its actual relationship or association since there is an existence of other confounders, variables or lifestyle with the exposure which might affect the subsequent disease condition. The results have not been consistent in the studies. Hypertension is one of the most significant etiological factors for cardiovascular diseases. Noise can cause high blood pressure mostly by two ways: either by releasing stress hormones like steroids or by stimulating sympathetic nervous system. China being one of the most rapidly developing countries in the world is having most prominent effect of noise in the daily life since it is a point for most of the goods manufacturing. Various national and international organizations like CDC, OSHA, and NIOSH etc. has recommended various ways to control the noise hazard and its deleterious impact on human health. This research was also done to assess the relationship or association between noise exposure level and prevalence of hypertension in the workers from steel factory in Guangzhou.

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Hypertension and Related Cardiovascular Disease Burden in China

Cited by 123 publications

References 33 publications

Nonspecific ST-T changes associated with unsatisfactory blood pressure control among adults with hypertension in China

Nonspecific ST-T changes associated with unsatisfactory blood pressure control among adults with hypertension in China

Interaction of heat shock protein 70 (HSP70) polymorphisms and occupational hazards increases the risk of hypertension in coke oven workers

Occupational Noise Exposure in Relation to Hypertension: A Cross-sectional Study in the Steel Factory

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