Hypertension Guidances Published in 2013: A Busy Year With More to Follow

Blood Pressure Measurement Modalities: A Primer for Busy Practitioners

“…There is no shortage of guidelines addressing out‐of‐office modalities, nor of discussions of them . Whatever the content of relevant guidelines, however, the advantages of a given modality can only be realized if that modality is available and employed.…”

Inferences Beyond a Study Design’s Grasp: A Cautionary Case Study From the Recent Renal Sympathetic Denervation Literature

“…2 They wish to bring appropriately safe and efficacious medical products to patients who need them as expeditiously as possible to promote public health, and regulatory science 3 can play an important role in this regard. However, regulatory agencies must also temper such legitimate and laudable desires with “calm, clinical, and comprehensive evaluations of approaches to any medical need.” 4 This Commentary is a cautionary tale not only for clinical researchers addressing legitimate and very important medical needs but also for regulatory agencies that must evaluate evidence presented to them by clinical researchers and determine if such research meets the evidentiary standards necessary for marketing approval. Our key message is simple, but we believe it is one that illuminates a grave and often overlooked principle: optimal study design in experimental clinical research is abandoned at one’s peril.…”