Hypertension in an Adult with Unilateral Renal Dysplasia.

Abstract

We report a 29-year-old Japanese female with severe hypertension and unilateral renal dysplasia, which is rarely found in adults. The involved kidney was surgically removed and then the blood pressure fell to borderline levels without any changes in plasma renin activity or plasma aldosterone concentration. Histological examinations revealed typical renal dysplasia without hyperplasia of the juxtaglomerular apparatus. Unilateral renal dysplasia may be a cause of secondary hypertension in adults, though the mechanisms are still unknown. (Internal Medicine 31: 530-533, 1992)

Renal Segmental Hypoplasia, Ask-Upmark Kidney, in a Patient with Adult-onset Hypertension

“…This renal anomaly is frequently unilateral, but bilaterally asymmetrical segmental hypoplasia has also been reported (4). In the present case, the right kidney showed the diffuse anomaly; thus there is a possibility that the right kidney lesions have might have been due to other renal anomalies, such as unilateral renal hypoplasia or renal dysplasia (5). Ask-Upmark kidney has come to be regarded as a consequence of vesicoureteral reflux rather than a true congenital malformation (2).…”