2006
DOI: 10.1002/1097-0142(19830701)52:1<169::aid-cncr2820520130>3.0.co;2-t
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Hypertension with renal carcinoma an effect of arterial embolization

Abstract: A patient presented with mediastinal metastases from renal adenocarcinoma. Palliative therapy included Gelfoam and steel coil embolization of the right renal artery. Six weeks later he was found to have developed severe hypertension. Arteriogram revealed collateral vessels which supplied the tumor; the renal vein renin activity was four times higher on the right than on the left. We suspect that infarction of the kidney was not complete because of collateral arterial supply, and renin‐dependent hypertension wa… Show more

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Cited by 5 publications
(2 citation statements)
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“…Two reports of a similar phenomenon can be found in the literature [6,7], but with the important distinguishing factor that unlike the cases we presented, they underwent complete renal arterial occlusion for renal cell carcinoma. In hypothesising the link between RAE and hypertension, we will initially review the potential effects of reduced blood supply on the RAS and the ischemic induced microvascular changes that may underline hypertension.…”
Section: Discussionsupporting
confidence: 68%
“…Two reports of a similar phenomenon can be found in the literature [6,7], but with the important distinguishing factor that unlike the cases we presented, they underwent complete renal arterial occlusion for renal cell carcinoma. In hypothesising the link between RAE and hypertension, we will initially review the potential effects of reduced blood supply on the RAS and the ischemic induced microvascular changes that may underline hypertension.…”
Section: Discussionsupporting
confidence: 68%
“…The pathogenesis of HTN following RAE is not clear, and the existing evidence appears to be limited to case reports and case series [14][15][16]. The kidneys play an integral role in the regulation of blood pressure and fluid balance.…”
Section: Discussionmentioning
confidence: 99%