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BACKGROUND Essential hypertension represents 90 – 95 % of all instances of hypertension. Microalbuminuria was observed to be related to increased chances of coronary artery disease even in patients already on treatment for hypertension. Microalbuminuria was identified with left ventricular hypertrophy recommending equal heart harm and albuminuria in hypertensive patients. However, the pervasiveness of hypertension is high in India, the connection between microalbuminuria and target organ damage in hypertension isn't well studied. This study intended to decide the extent of microalbuminuria in non-diabetic patients with essential hypertension and concentrate on the relationship of microalbuminuria with the worsening of left ventricular hypertrophy (LVH) and hypertensive retinopathy (HRP). METHODS This was a hospital-based cross-sectional analysis conducted in a hospital from January 2019 to September 2019. Information was gathered from 93 patients fulfilling the consideration standards utilizing a formerly planned semi-structured questionnaire. Urine microalbumin level, echocardiography, ECG and fundus assessment were done. The study variables were recorded and dissected utilizing SPSS software. RESULTS The mean age of the group populace was 55 + 8.89 years. Microalbuminuria was present in 68 %. There was a measurably critical relationship between the age group studied and the predominance of microalbuminuria. There was a huge factual affiliation between the presence of microalbuminuria and LVH in hypertensive patients (P < 0.0001), with microalbuminuria and HRP (P < 0.0001) and with microalbuminuria and long-standing hypertensives (P < 0.0001). CONCLUSIONS The larger part of microalbuminuria positives was found disseminated among higher ages. There was a positive relationship among patients with microalbuminuria and LVH, with retinopathy in hypertensive patients, with grade 2 hypertension and with long-standing hypertensives. KEY WORDS Hypertension, Microalbuminuria, LVH, Hypertensive Retinopathy
BACKGROUND Essential hypertension represents 90 – 95 % of all instances of hypertension. Microalbuminuria was observed to be related to increased chances of coronary artery disease even in patients already on treatment for hypertension. Microalbuminuria was identified with left ventricular hypertrophy recommending equal heart harm and albuminuria in hypertensive patients. However, the pervasiveness of hypertension is high in India, the connection between microalbuminuria and target organ damage in hypertension isn't well studied. This study intended to decide the extent of microalbuminuria in non-diabetic patients with essential hypertension and concentrate on the relationship of microalbuminuria with the worsening of left ventricular hypertrophy (LVH) and hypertensive retinopathy (HRP). METHODS This was a hospital-based cross-sectional analysis conducted in a hospital from January 2019 to September 2019. Information was gathered from 93 patients fulfilling the consideration standards utilizing a formerly planned semi-structured questionnaire. Urine microalbumin level, echocardiography, ECG and fundus assessment were done. The study variables were recorded and dissected utilizing SPSS software. RESULTS The mean age of the group populace was 55 + 8.89 years. Microalbuminuria was present in 68 %. There was a measurably critical relationship between the age group studied and the predominance of microalbuminuria. There was a huge factual affiliation between the presence of microalbuminuria and LVH in hypertensive patients (P < 0.0001), with microalbuminuria and HRP (P < 0.0001) and with microalbuminuria and long-standing hypertensives (P < 0.0001). CONCLUSIONS The larger part of microalbuminuria positives was found disseminated among higher ages. There was a positive relationship among patients with microalbuminuria and LVH, with retinopathy in hypertensive patients, with grade 2 hypertension and with long-standing hypertensives. KEY WORDS Hypertension, Microalbuminuria, LVH, Hypertensive Retinopathy
The aim: To examine the association of hypertensive mediated target organ damage with blood pressure visit-to-visit variability in Ukrainian rural dwellers with uncomplicated hypertension. Material and methods: The cross-sectional study enrolled 160 adult males with uncomplicated primary hypertension (mean age 50±6 yo). We analyzed office systolic and diastolic blood pressure levels, obtained at four consecutive visits. We used standard deviation (SD) value to assess blood pressure visit-to-visit variability. The patients were referred to the group with high (n=82; 51.3%) vs low (n=78; 48.7%) blood pressure variability (HBPV, LBPV). Results: HBPV patients were characterized by higher left ventricular myocardial mass indexed to height 2.7: median, interquartile range: 70.9 (61.3-78.2) vs 50.9 (44.9-54.4) g/m2.7, respectively p<0.001. The cases of severe left ventricular hypertrophy prevailed in HBPV group (vs LBPV): 68% vs 5%, respectively, p<0.001. HBPV group was characterized by larger common carotid artery intima-media complex thickness, advanced hypertensive retinopathy, higher urine albumin/creatinine ratio value and worse kidneys’ glomerular filtration rate. The obtained results might be helpful in the context of global monitoring of vulnerable high risk population of hypertensive rural males. Conclusions: The HBPV in rural hypertensive males was associated with more pronounced target organ damage. Further regional research on the various clinical aspects of hypertension, including blood pressure variability, might be useful in extending the existed evidence on prevention of hypertension-related complications.
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