Hypertrichosis lanuginosa acquisita

Abstract

The purpose of this report is to give further details of a case of hypertrichosis lanuginosa acquisita, previously documented as not having an associated malignancy, which at post-mortem was found to have evidence of widespread internal malignant disease.

Diseases of cutaneous appendages

“…An important cause is an underlying cancer, usually of epithelial type, 1179 although rarely a lymphoma is present. 1181,1182 There may be rapid resolution after treatment of the malignancy. 1181,1182 There may be rapid resolution after treatment of the malignancy.…”

Acquired Hypertrichosis lanuginosa: A Case Report

“…In one patient, only a post-mortem re vealed an infiltrating tumor of the right main bronchus [3]. Our case can be included in one of the last two groups.…”

Acquired hypertrichosis lanuginosa: Case report and review of the literature

“…AHL may be associated with several manifestations, including burning glossitis [8,12,13,29,33], papillary hypertrophy of the tongue [20], disturbances of taste [40] and smell, diarrhea [18,31], adenopathy, and weight loss [2], and other skin anomalies such as scleroderma [17], acanthosis nigricans [10,38], and seborrheic keratoses [30].…”

“…Since 1865, approximately 50 cases have been described in the literature, usually associated with malignant diseases [2,3]. Malignant neoplasms more frequently associated with AHL include lung cancer [4][5][6][7][8][9][10][11][12][13][14][15][16][17] and colorectal carcinomas [18][19][20][21][22][23][24][25][26][27][28], but it has also been described in association with lymphomas [29,30] as well as carcinomas of the kidney [31], pancreas [32], breast [1,[33][34][35], uterus [29,36,37], ovary [38], bladder [39], gallbladder [40], leukemia [41], and liver metastatic adenocarcinoma [42]. In women with AHL, the more frequent malignancy is colorectal cancer, followed in order of frequency by lung cancer and breast cancer; in men, lung cancer is the malignancy most frequently associated with AHL, followed by colorectal cancer.…”