Hyperuricaemia and its association with other risk factors for cardiovascular diseases: A population‐based study

Yazdi, Farzaneh; Shakibi, Mohammad Reza; Baniasad, Amir; Najafzadeh, Mohammad Javad; Najafipour, Hamid; Yazdi, Fatemeh; Sistani, Samira

doi:10.1002/edm2.387

Cited by 3 publications

(1 citation statement)

References 26 publications

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“…Hyperuricemia is a disease marked by unusually high serum uric acid levels ( 2 ), which can cause several diseases linked to crystal deposits, including uric acid nephropathy, gout, and urolithiasis ( 3 ). Many epidemiological studies have pointed out that hyperuricemia is intimately linked to the development of cardiovascular diseases ( 4 ), diabetes mellitus (DM) ( 5 ), hypertension ( 6 ), and dyslipidemia ( 7 ). It is one of the most common metabolic disorders in modern times with a heavy health and economic burden.…”

Section: Introductionmentioning

confidence: 99%

Association between nocturnal sleep duration and the risk of hyperuricemia among Chinese government employees: A cross-sectional study

Ouyang

et al. 2022

Front. Public Health

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ObjectivesEvidence has shown that nocturnal sleep duration is associated with the risk of hyperuricemia, yet the findings are inconsistent. Thus, we aimed at exploring the association between nocturnal sleep duration and the risk of hyperuricemia in Chinese government employees.MethodsA total of 10,321 government employees aged 20–60 years were collected from the Cohort Study on Chronic Diseases among Government Employees in Hunan Province, China. Sleep duration was self-reported. And serum uric acid levels >420 μmol/L in men and >360 μmol/L in women were considered hyperuricemia. The association between nocturnal sleep duration and hyperuricemia risk was examined utilizing multivariate logistic regression models. To further examine the connection between nocturnal sleep duration and serum uric acid levels, multiple linear regression analyses were utilized.ResultsThe prevalence of hyperuricemia was 17.2%. The results of logistic regression demonstrated that, in contrast to participants whose sleep duration was 7–8 h, those who slept for <7 h had an elevated risk of hyperuricemia (OR = 1.343, 95%CI: 1.126, 1.601). Further stratified analysis revealed that this association was still observed in those without obesity (OR = 1.365; 95%CI: 1.127, 1.655), hypertension (OR = 1.290, 95%CI: 1.054, 1.578), or diabetes mellitus (OR = 1.361, 95%CI: 1.136, 1.631). Multiple linear regression showed that shorter sleep duration (< 7 h) was positively correlated with serum uric acid levels. In comparison to individuals who slept for 7–8 h, those with sleep duration of fewer than 7 h had serum uric acid levels that were 7.231 μmol/L (95% CI: 2.875, 11.588) higher.ConclusionShort nocturnal sleep duration (< 7 h) was associated with a higher risk of hyperuricemia, especially in participants without obesity, hypertension, or diabetes mellitus. Besides, short nocturnal sleep duration was related to greater uric acid levels.

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Section: Introductionmentioning

confidence: 99%

Association between nocturnal sleep duration and the risk of hyperuricemia among Chinese government employees: A cross-sectional study

Ouyang

et al. 2022

Front. Public Health

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Hyperuricaemia and its association with other risk factors for cardiovascular diseases: A population‐based study

Yazdi

Shakibi

Baniasad

et al. 2022

Endocrino Diabet & Metabol

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The prevalence of metabolically healthy obesity and its transition into the unhealthy state: A 5‐year follow‐up study

Baniasad,

Najafzadeh,

Najafipour

et al. 2024

Clinical Obesity

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SummaryPeople with metabolically healthy obesity (MHO) are at risk of developing cardiometabolic diseases. We investigated the prevalence of MHO and factors influencing its transition into a metabolically unhealthy state (MUS). This study was conducted as part of the Kerman Coronary Artery Disease Risk Factor Study (KERCADRS). From 2014 to 2018, 9997 people were evaluated. The obesity and metabolic status of the MHO participants were re‐examined after 5 years of their initial participation in the study. Out of 347 MHO, 238 individuals were accessed at follow‐up. Twenty‐nine (12.2%) had metabolic unhealthy normal weight (MUNW), 169 (71.0%) had metabolic unhealthy obesity (MUO), and the others had healthy metabolic state. Among age, total cholesterol, diastolic blood pressure and triglyceride (TG) variables, the baseline serum TG level was associated with a significant increase in the risk of developing MUS during 5 years (p <.05). The TG level optimal cut‐off point for predicting the development into MUS was 107 mg/dL with 62.1% sensitivity and 77.5% specificity (AUC = 0.734, p <.001). A high percentage of MHO people transit into MUS during 5 years. A TG level higher than 107 mg/dL can help to identify people at a higher risk of developing into MUS.

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Hyperuricaemia and its association with other risk factors for cardiovascular diseases: A population‐based study

Abstract: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Cited by 3 publications

References 26 publications

Association between nocturnal sleep duration and the risk of hyperuricemia among Chinese government employees: A cross-sectional study

Association between nocturnal sleep duration and the risk of hyperuricemia among Chinese government employees: A cross-sectional study

Hyperuricaemia and its association with other risk factors for cardiovascular diseases: A population‐based study

The prevalence of metabolically healthy obesity and its transition into the unhealthy state: A 5‐year follow‐up study

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