Hyperuricemia and Associated Factors during Arterial Hypertension in Brazzaville (Congo)

Abstract

A longitudinal analytical and comparative study including outpatients was carried between June 1 st and December 31 st 2017. The objectives were to determine the hyperuricemia frequency during arterial hypertension, to identify associated factors, and to evaluate its impact on the blood pressure control. We have included, hypertensive patients having a minimum blood test including at least an uricemia. They were divided into two groups according to whether they have presented a hyperuricemia (HU) or a normouricemia (NU). Among these 202 patients included, 61 (30.2%) presented a hyperuricemia. The mean age in HU group was 54.6 ± 11.6 years vs 53.6 ± 11 years for NU group (p = 0.573). Following cardiovascular risk factors were more found in the HU group than NU group: overweight/obesity (68.8% vs 46.1%; p = 0.003), metabolic syndrome (42.6% vs 39%; p = 0.021). Diuretics were used in 72.1% of patients in HU group vs 47.5% in NU group (p = 0.002). Bitherapy was used in 56% of the patients of HU group vs 69% in the NU group (p = 0.295), and the quadritherapy in 8% and 1% of the patients respectively (p = 0.049). Blood pressure was not controlled in 68.8% of HU group vs 48.9% in the NU group (p = 0.014). In multivariate analysis after logistic regression, factors associated with hyperuricemia were: glucose intolerance or diabetes (p = 0.004; OR = 1.35) and uncontrolled blood pressure (p = 0.006; OR = 2.51). This preliminary study showed that hyperuricemia is commonly found in hypertensive patients and has negative impact on blood pressure control.

Epidemiological, Clinical, Therapeutic, and Evolutionary Aspects of Heart Failure in the Medical Department at Gao Regional Hospital

“…This rate is higher than those reported by several studies such as in Libreville (10.3%) and Rabat (6.1%) [3] [23]. Our rate was lower than that collected in Brazzaville (20.2%) among elderly people with an estimated average age of 70.4 years [11]. This difference in frequency could take place, on the one hand, by the fact that ours was carried out in a medical structure without a cardiology intensive care unit, let alone a cardiac catheterization room, like the studies carried out at the University Hospitals of Libreville and Rabat.…”

“…The role of traditional therapists plays a significant role, an observation also made by some authors [4]. The main etiologies were dominated by hypertensive heart disease, this etiology was widely found in several [3] [4] [11] [13] [14]. The THESUS-HF study carried out in nine sub-Saharan countries also highlighted the supremacy of hypertensive heart disease in our countries [19].…”

Incidence and impact of cardio-renal syndrome type 1 in patients with heart failure

“…The main electrocardiographic anomaly found is complete arrhythmia due to atrial fibrillation with a percentage significantly higher than that found by Awa THIAW (11.1%) as well as Ikama MS and his collaborators (14.35%) [17,18]. LVEF, an important index of severity and poor prognosis of heart failure, was altered in more than two-thirds of patients, whereas McAlister et al found in their study carried out in the cardiology department in CANADA in 2004 an altered LVEF in 57% [19].…”