Hyperuricemia and its related factors in an urban population, Izmir, Turkey

Sarı, İ̇smail; Akar, Servet; Pakoz, Betul; Şişman, Ali Rιza; Gürler, Oğuz; Bırlık, Merih; Önen, Fatoş; Akkoç, Nurullah

doi:10.1007/s00296-008-0806-2

Cited by 48 publications

(41 citation statements)

References 15 publications

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“…In Brazil, there are no available data from population-based epidemiological studies on the occurrence of altered serum uric acid levels. Despite the recognition of the limitations in the direct comparison between findings from the current study and those of other researchers (particularly because of the different age structures in these population groups and the different approaches used), one can state that the prevalence of hyperuricemia detected among Japanese-Brazilians (35.3%) was higher than described in international studies 11,35,36 . As identified in previous publications by the JBDSG 19,21,33,34 , this community also displays high rates of co-morbidities associated with hyperuricemia, thus characterizing high risk for cardiovascular diseases.…”

Section: Discussioncontrasting

confidence: 76%

Hyperuricemia and associated factors: a cross-sectional study of Japanese-Brazilians

et al. 2011

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IntroductionThe scientific literature makes widespread reference to the association between chronic noncommunicable diseases, especially rheumatic and cardiovascular diseases, and hyperuricemia 1,2,3 . The relationship between excess plasma uric acid and gout is described in the literature, but despite all the studies and technological advances, there is still limited evidence to show a direct relationship between hyperuricemia and cardiovascular diseases 3,4,5 .According to previous studies, some foods can help increase or decrease the serum uric acid levels 6,7,8 , depending on their purine content. There is still little information on the exact amount of purines contained in foods, since their content and availability depend on the food processing procedures, among other factors 4,9,10 .Various studies 3,8,11,12,13 have pointed to excessive intake of fat, alcohol, and fructose, as well as changes in body weight (both excess weight and sudden weight loss) as risk factors for hyperuricemia. In addition, a reduction in the consumption of protein-rich foods (especially animal protein) can help decrease the blood uric acid levels 11,13 . The literature includes reports that excess body fat may be the most important nutritional factor for hyperuricemia 2,4,14 .According to previous publications, hyperuricemia is associated with various chronic diseases such as arterial hypertension, cardio-ARTIGO ARTICLE Poletto J et al. 370 Cad. Saúde Pública, Rio de Janeiro, 27(2):369-378, fev, 2011

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Section: Discussioncontrasting

confidence: 76%

Hyperuricemia and associated factors: a cross-sectional study of Japanese-Brazilians

et al. 2011

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“…Studies on the prevalence of MetS in Turkey ranges from 26.5% to 42.6% (6)(7)(8). Recent studies have shown that the prevalence of MetS and cardiovascular diseases (CVDs) increases in patients with PsA and that CVDs are the most common cause of death in patients with PsA (9)(10)(11)(12)(13)(14).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of metabolic syndrome and degree of cardiovascular disease risk in patients with Psoriatic Arthritis

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Behlül

et al. 2017

Eur J Rheumatol

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Objective: The aim of this study was to identify the prevalence of metabolic syndrome (MetS) and degree of cardiovascular disease (CVD) risk in patients with psoriatic arthritis (PsA). Material and Methods:We performed a cross-sectional study on 102 adult patients with PsA and a control group of 102 patients with rheumatoid arthritis (RA). MetS was diagnosed according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III) and International Diabetes Federation (IDF) criteria. The Framingham risk scores of 10-year risk of CVDs and coronary heart disease (CHD) were also calculated.Results: The prevalence of MetS was higher in patients with PsA than in those with RA, according to the NCEP-ATP III (40.6% vs.24.7%, respectively; p=0.019) and IDF (46.8% vs. 27.9%, respectively; p=0.05) criteria. The prevalence of MetS was higher in female patients with PsA (p=0.009) than in male patients. A significantly increased prevalence of hypertriglyceridemia was determined in patients with PsA (p=0.019). No significant difference existed between the two groups with respect to 10-year CVD (p=0.333) and CHD (p=0.798) risks. Additionally, there were no significant differences between the clinical subtypes of PsA with regard to MetS (p=0.229). Conclusion:MetS prevalence increased in patients with PsA compared with those with RA, whereas the risks were similar for CVDs and CHD. For this reason, optimal protection measures should be taken and guidelines should be applied to achieve adequate metabolic control in patients with PsA.

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“…Obesity is closely related to hyperuricemia, as increased levels of insulin in obese subjects were associated with an enhanced sodium and uric acid reabsorption. 19 Measures of obesity including BMI and waist circumference Interaction between serum uric acid and triglycerides F Teng et al have been shown to be independent predictors of hyperuricemia, 20 and BMI showed a positive correlation with uric acid levels. 19 However, our study did not find significant interactions between uric acid status and BMI after stratified analysis.…”

Section: Discussionmentioning

confidence: 99%

Interaction between serum uric acid and triglycerides in relation to blood pressure

et al. 2010

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The aim of this study was to examine the independent relationship between serum uric acid (SUA) and blood pressure, and to assess their joint effects on obesity, fasting glucose and lipids. The study samples were from a community-based health examination survey in Xuzhou, Jiangsu province of China (2009). Blood pressure, body mass index, fasting glucose, lipids and SUA were measured. After excluding individuals with fasting glucose greater than 7 mmol l À1 , a total of 8415 subjects with biomarkers available were included in the present study. Blood pressure increased with elevated SUA levels, after adjusting for age and sex. Further adjustment for fasting glucose, lipids and alcohol consumption did not change the increasing trend. The associations between uric acid and hypertension were most evident in those with highest quintiles of high-density lipoprotein cholesterol (HDL-C). In addition, the associations were significant in both men and women, and we found significant interactions between uric acid status and age on hypertension. When the joint effects were examined, we found an additive effect of triglycerides and uric acid levels on diastolic blood pressure (DBP). There was significant association between SUA and hypertension, independent of other metabolic risk factors. HDL-C levels may modify the associations between uric acid and hypertension. The effects of triglycerides and uric acid levels on DBP were additive.

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Hyperuricemia and its related factors in an urban population, Izmir, Turkey

Cited by 48 publications

References 15 publications

Hyperuricemia and associated factors: a cross-sectional study of Japanese-Brazilians

Hyperuricemia and associated factors: a cross-sectional study of Japanese-Brazilians

Prevalence of metabolic syndrome and degree of cardiovascular disease risk in patients with Psoriatic Arthritis

Interaction between serum uric acid and triglycerides in relation to blood pressure

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