2008
DOI: 10.1016/j.fitote.2008.04.002
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Hypoglicemic effect of Leandra lacunosa in normal and alloxan-induced diabetic rats

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Cited by 45 publications
(29 citation statements)
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“…Muitas espécies da família Melastomataceae possuem ação antibacteriana (Wang et al, 2008), hipoglicemiante (Cunha et al, 2008), anti-inflamatória e analgésica (Nualkaew et al, 2009), e algumas espécies são utilizadas no tratamento de dor gástrica e gastrite, dispepsia, verminoses, escabiose e hipertensão (Silva et al, 2000;Cruz, 2004).…”
Section: Introductionunclassified
“…Muitas espécies da família Melastomataceae possuem ação antibacteriana (Wang et al, 2008), hipoglicemiante (Cunha et al, 2008), anti-inflamatória e analgésica (Nualkaew et al, 2009), e algumas espécies são utilizadas no tratamento de dor gástrica e gastrite, dispepsia, verminoses, escabiose e hipertensão (Silva et al, 2000;Cruz, 2004).…”
Section: Introductionunclassified
“…One of phenomenon of type 2 diabetes is insulin insensitivity which has negative metabolic consequences [5,7] and contributes subsequent pancreas β-cell exhaustion, resulting in the onset of clinical hyperglycemia. It has been reported that flavonoids has a role in regeneration of the injured pancreatic β-cells in diabetic models [25] and thus may prevent insulin resistance.…”
Section: Discussionmentioning
confidence: 99%
“…Environmental pollutants, side effects of drug metabolism, smoking, alcohol, inadequate nutrition, and excess solar radiation are known sources for ROS during diabetes [4] which, in turn, increase dyslipidemia. On the other hand, early phenomenon of type 2 diabetes mellitus is insulin insensitivity which not only has negative metabolic consequences [5,6] but it also contributes subsequent pancreas β-cell exhaustion, resulting in the onset of clinical hyperglycemia [7].…”
Section: Introductionmentioning
confidence: 99%
“…Make use of onion and Quercetin in diabetic patient treatment has been experimented [11] . Investigations show onion and Quercetin decrease serum glucose level [12 ] but this reduction with onion has been significant [13] . Also Quercetin decreases oxidative stress and blood vessels damage in diabetic rats [14] .…”
Section: Discussionmentioning
confidence: 99%