Hypogonadism in aged hospitalized male patients: prevalence and clinical outcome

Hypogonadism and Mortality in Aged Hospitalized Male Patients: A 5-Year Prospective Observational Study

“…As previously reported [11], hypogonadism at entry was associated with a personal history of heart disease (heart failure, angina pectoris and/or acute myocardial infarction) (P < 0.032), cancer (P = 0.004), respiratory pathology (P = 0.016), and renal insufficiency (P = 0.013). The main cause of admission in hypogonadic patients was respiratory tract infection ( Table 1.…”

“…Hypogonadism in aged hospitalized male patients is a common event. In fact, as we have previously reported [11], hypogonadism, mainly non-hypergonadotropic type, was present in about half of the patients (80 patients, 53.3 %), indicating predominantly a central (hypothalamic or pituitary) failure. Although a high prevalence of hypogonadism is expected in the elderly [13][14][15], the coexistence of acute and chronic illnesses, and perhaps polymedication might have positively influenced on the elevated prevalence.…”

“…Hypogonadal patients were subsequently classified in the subgroups of hypergonadotropic, normogonadotropic and hypogonadotropic hypogonadism, according to their levels of FSH and LH (elevated, normal or decreased, respectively). Clinical features of the patients, main causes of hospital admission, and diagnostic criteria for primary and secondary hypogonadism were as previously reported [11,12].…”

“…A 5-year (from January 1 st , 2010 to January 1 st , 2015) prospective observational study including all patients older than 65 years hospitalized due to an acute process during 2010 and 2011 was carried out. Patients were recruited from a previous crosssectional study [11]. All admitted patients in our geriatric unit were included in the study regardless of the cause of hospitalization.…”

Cross‐Sectional, Primary Care–Based Study of the Prevalence of Hypoandrogenemia in Nondiabetic Young Men with Obesity

“…Although the prevalence of hypoandrogenemia described in this study was lower than that previously described in men with obesity, it is important to take into account that the design of our study was clearly different from previous studies: we included only patients < 50 years of age to limit the well-known deleterious effect of age on testosterone levels (21,22), and patients with T2DM, CVD, and other chronic diseases (conditions directly associated with a reduction in testosterone levels) (23,24) were also excluded. In fact, in a recent study performed by Lotti et al (25), men with metabolically complicated obesity (described as BMI ≥ 30 with hypertension or BP > 130/80 mm Hg, high-density lipoprotein cholesterol < 40 mg/dL, or T2DM) had a higher risk of secondary hypogonadism compared with participants with metabolically healthy obesity (described as BMI ≥ 30 without any metabolic abnormalities).…”