Hypomagnesemia and Ventricular Tachycardia

Magnesium Deficiency: A Cause of Heterogenous Disease in Humans

“…Supraventricular arrhythmias such as premature atrial complexes, atrial tachycardia, atrial fibrillation, and junctional arrhythmias have been described (109) . Ventricular dysrhythmias include premature contraction, ventricular tachycardia, and fibrillation (110–113) . The frequency of ventricular arrhythmias occurring post–myocardial infarction also appears to be increased in hypomagnesemic patients, and may be decreased with magnesium therapy (114–118) .…”

Alteration in Mg2+content of red blood cells from patients with diuretic therapy

“…There are no detailed comparative studies on intracellular Mg 2+ content using newer loop diuretics. As plasma Mg 2+ concentrations constitute only about 3% of total body Mg 2 § , intracellular Mg 2+ concentrations are of special interest, especially in patients with cardiac arrhythmias, necrosis, or hereditary cardiomyopathy [8][9][10]14,15].…”

“…33, 48149 Mtinster, Germany is of special interest because body Mg z § stores cannot be assessed adequately by measurements of plasma Mg 2+ concentrations as blood plasma contains less than 3% of body Mg 2+ [6,7]. Furthermore, a Mg 2+ depletion can be associated with an increased frequency of cardiac arrhythmias, ventricular tachycardia, or torsades de pointes [8][9][10]. In earlier literature there are few studies comparing intracellular Mg z+ content during treatment with different diuretics [1,2,11,12].…”

Effectiveness of Oral Magnesium in a Patient With Ventricular Tachycardia Due to Hypomagnesemia

“…Further evaluation is thus required to exclude underlying cardiac disease or the presence of other risk factors. Hypomagnesemia alone is not usually associated with cardiac arrhythmia (2), but treatment with intravenous magnesium has reportedly ameliorated ventricular arrhythmia in some cases (3). We present a patient with ventricular tachycardia due to hypomagnesemia, in whom ventricular tachycardia was resolved after treatment with oral magnesium hydroxide.…”