Hypopigmented parapsoriasis en plaque, a new, overlooked member of the parapsoriasis family: A report of 34 patients and a 7-year experience

El-Darouti, Mohammad Ali; Fawzy, Marwa M.; Hegazy, Rehab A.; Hay, Rania Abdel

doi:10.1016/j.jaad.2012.02.030

Cited by 11 publications

(7 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Se ha considerado una variante de la arapsoriasis de pequeñas placas (PPP). 11 Finalmente, la eritrodermia clonal, crónica y recalcitrante, se parece mucho a la eritrodermia del síndrome de Sézary, excepto en que carece de una cuenta de células de Sézary mayor de 1000 por mm 2 en sangre periférica y de una relación de CD4:CD8 mayor de 10:1. Los pacientes tienen prurito importante, queratodermia palmoplantar, ectropión, distrofia ungueal y alopecia.…”

Section: Discussionunclassified

“…el 35 % en PGP. 11 El objetivo del tratamiento de estos pacientes con fototerapia fue llevarlos a un estado de remisión completa. Es también objetivo del tratamiento el conseguir que los periodos de remisión sean lo más largos posible para que las recaídas se presenten lejanamente, y que si estas se van a presentar, sean de la misma o menor intensidad.…”

Section: Conclusiónunclassified

See 1 more Smart Citation

Discrasia linfoide epiteliotrópica de células T. Tratamiento con radiación ultravioleta

Lacy-Niebla

Toussaint–Caire

Mares-Navarro

2018

GMM

View full text Add to dashboard Cite

Introducción: Las discrasias linfoides epiteliotrópicas de células T son un grupo de dermatosis inflamatorias poco frecuentes que pueden progresar a linfomas cutáneos. El tratamiento con radiación ultravioleta ha sido descrito como seguro y eficaz. Objetivo: Describir la respuesta al tratamiento, sus efectos secundarios y complicaciones. Método: Se administró radiación ultravioleta A con psoralenos (PUVA) a dos pacientes y radiación ultravioleta B de banda estrecha (NB-UVB) a nueve pacientes, con diferentes discrasias. Resultados: Conformaron la serie siete mujeres y cuatro hombres, con edades de 5 a 30 años y con fototipos III y IV, con diagnóstico de discrasia linfoide epiteliotrópica hipopigmentada, pitiriasis liquenoide crónica, parapsoriasis hipopigmentada y púrpura pigmentada. Dos recibieron PUVA y nueve recibieron NB-UVB. Ocho alcanzaron respuesta completa y tres respuesta parcial con 10 a 119 sesiones de tratamiento. Ningún paciente presentó reactivación de la enfermedad después de 34 a 247 sesiones, y ninguno en tratamiento o seguimiento evolucionó a linfoma cutáneo. Los efectos secundarios fueron xerosis y prurito. Conclusión: El tratamiento de las discrasias linfoides con radiación ultravioleta es eficaz y seguro, con efectos secundarios leves y con respuestas exitosas en la mayoría de los pacientes, en tiempo y número de sesiones variables.

show abstract

Section: Discussionunclassified

Section: Conclusiónunclassified

Discrasia linfoide epiteliotrópica de células T. Tratamiento con radiación ultravioleta

Lacy-Niebla

Toussaint–Caire

Mares-Navarro

2018

GMM

View full text Add to dashboard Cite

show abstract

“…A diagnosis was given to each case based on constellation of clinical and histopathological findings and according to criteria described in the literature. 3,4,[7][8][9][10][11][12][13][14] Data were coded and entered using Statistical Package for Special Science (SPSS) software computer program version 15. Data were described as mean 6 SD for quantitative (numerical) variables and as frequency and percentage for qualitative (categorical) variables.…”

Section: Methodsmentioning

confidence: 99%

“…However, overdiagnosis of HMF can lead to unnecessary aggressive therapies. 2 Many skin diseases present with hypopigmented lesions that can be confused with HMF, such as vitiligo, leprosy, postinflammatory hypopigmentation, pityriasis alba, tinea versicolor, sarcoidosis, hypopigmented parapsoriasis en plaque, 3 and progressive macular hypomelanosis. 4 The aim of this work was to study the frequency of HMF in a cohort of Egyptian patients presenting to a tertiary care center in Cairo with hypopigmented lesions of the trunk.…”

Section: Introductionmentioning

confidence: 99%

Frequency of Hypopigmented Mycosis Fungoides in Egyptian Patients Presenting With Hypopigmented Lesions of the Trunk

Abdel‐Halim

El‐Nabarawy

Nemr³

et al. 2015

The American Journal of Dermatopathology

View full text Add to dashboard Cite

Hypopigmented mycosis fungoides (HMF) is an uncommon variant of mycosis fungoides with an unknown exact frequency. We aimed to study the frequency of HMF in a cohort of Egyptian patients presenting to a tertiary care center in Cairo, Egypt, with hypopigmented lesions of the trunk. Hundred patients with hypopigmented lesions involving the trunk (with or without other sites involvement) were subjected to thorough clinical and histopathological examination. Immunohistochemical studies (S100, CD4, and CD8) were performed when indicated. Constellation of findings was used to reach a final diagnosis. Sixteen cases had HMF (16%). Other than HMF, our cohort included hypopigmented parapsoriasis en plaque (42 cases), postinflammatory hypopigmentation (28 cases), progressive macular hypomelanosis (12 cases), and pityriasis alba (2 cases). In comparison with other hypopigmented disorders, HMF was significantly associated with progressive disease course (P = 0.004), affection of distal upper limbs (P = 0.005), proximal lower limbs (P = 0.003), large-sized lesions (>5 cm) (P < 0.0001), well-defined margin (P < 0.0001), scaliness (P = 0.002), erythema (P < 0.0001), atrophy (P = 0.012), and mottled pigmentation (P < 0.0001). Awareness of HMF and its characteristic clinical features is mandatory to avoid underdiagnosis or overdiagnosis with subsequent morbidity or unnecessary aggressive therapy, respectively.

show abstract

“…However, any site may be involved, and pruritus is a variable feature 49 . It may be diagnosed late as it resembles many benign dermatoses in childhood like pityriasis alba, atopic dermatitis, tinea versicolor, post‐inflammatory hypopigmentation, or other conditions like vitiligo, leprosy, sarcoidosis, hypopigmented parapsoriasis en plaque, and progressive macular hypomelanosis 48,50 . Among Fitzpatrick skin type IV to VI, hypopigmented MF is more commonly seen in children, and it usually presents at a younger age as compared to children with other variants of MF 8,30,51 …”

Section: Clinical Presentationmentioning

confidence: 99%

Mycosis fungoides in pediatric population: comprehensive review on epidemiology, clinical presentation, and management

et al. 2022

View full text Add to dashboard Cite

Mycosis fungoides (MF) is the most common type of cutaneous T‐cell lymphoma. However, it is rare in pediatric population. Most of the cases of pediatric MF present with hypopigmented patches and/or various other forms, which may often mimic common childhood dermatoses, thereby causing a delay in the diagnosis. There are no established treatment guidelines for pediatric MF. As the progression of childhood MF is extremely rare and it has an indolent course, it is usually diagnosed at an early stage (IA, IB, IIA), and hence phototherapy with a response rate of >80% is a well‐established effective treatment in children. However, as recurrences are frequently seen on stopping the therapies, a maintenance regimen and long‐term follow‐up is equally important. This article reviews the epidemiological factors, clinical presentations, diagnosis, and various treatment modalities used in pediatric MF. We analyzed and compared the data of almost 616 childhood MF cases from various studies undertaken from 1988 to 2021.

show abstract

Hypopigmented parapsoriasis en plaque, a new, overlooked member of the parapsoriasis family: A report of 34 patients and a 7-year experience

Cited by 11 publications

References 19 publications

Discrasia linfoide epiteliotrópica de células T. Tratamiento con radiación ultravioleta

Discrasia linfoide epiteliotrópica de células T. Tratamiento con radiación ultravioleta

Frequency of Hypopigmented Mycosis Fungoides in Egyptian Patients Presenting With Hypopigmented Lesions of the Trunk

Mycosis fungoides in pediatric population: comprehensive review on epidemiology, clinical presentation, and management

Contact Info

Product

Resources

About