Hypothermia in Trauma Victims

Jurkovich, Gregory J.; Greiser, W. B.; Luterman, Arnold; Curreri, P. William

doi:10.1097/00005373-198709000-00011

Cited by 600 publications

(48 citation statements)

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“…In the developed countries, injury constitutes the leading causes of death among people aged 15-44 years and is increasingly a leading cause of death in the low-and middle-income countries, where death due to infection is also high (3) . Trauma victims often suffer from hypothermia on arrival at hospital and, even when the hypothermia is moderate; it can be associated with a poorer prognosis and an increase in mortality rate (4)(5)(6)(7)(8)(9)(10)(11) . Hypothermia is commonly found in injured victims and occurs in about 57% trauma admission in Accident & Emergency Department (16) .…”

Section: …………………………………………………………………………………………………… Introduction:-mentioning

confidence: 99%

“…However, although the mechanisms of the deleterious effects of hypothermia are well known, its causes are not clear. Most published data on hypothermia victims are hospital registry data or data from retrospective studies (6)(7)(8)(9)(10)(11)(12)(13) .…”

Section: …………………………………………………………………………………………………… Introduction:-mentioning

confidence: 99%

“…A possible cause of hypothermia is the severity of the injury (4,(6)(7)(8)(9)(10)(11)14) . Both severe head injury and hypovolemic shock affect body temperature regulation.…”

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confidence: 99%

“…In trauma, several retrospective studies have found an association between higher death rate and an increasing degree of hypothermia, even accounting for differences in the severity of injury (7,11) . Jurkovich et al (7) found that no trauma patient whose core temperature fell below 32 °C survived, and they regarded this as the critical temperature for survival.…”

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confidence: 99%

“…Jurkovich et al (7) found that no trauma patient whose core temperature fell below 32 °C survived, and they regarded this as the critical temperature for survival. Hypothermia is recognized as one pillar of a -lethal triad‖ (hypothermia, acidosis and coagulopathy) of homeostatic failure that is believed to mark the limits of ongoing intervention, and necessitates an -abbreviated‖ laparotomy (26)(27)(28)(29)(30) .…”

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confidence: 99%

See 4 more Smart Citations

Systematic Review of Evidence-Based in Beneficial Preventing Hypothermia for Adult Trauma Patients in Accident.

Alghamdi.¹,

Alaklabi.²,

Alanazi.³

et al. 2017

IJAR

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Section: …………………………………………………………………………………………………… Introduction:-mentioning

confidence: 99%

Section: …………………………………………………………………………………………………… Introduction:-mentioning

confidence: 99%

“…A possible cause of hypothermia is the severity of the injury (4,(6)(7)(8)(9)(10)(11)14) . Both severe head injury and hypovolemic shock affect body temperature regulation.…”

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 3 more Smart Citations

Systematic Review of Evidence-Based in Beneficial Preventing Hypothermia for Adult Trauma Patients in Accident.

Alghamdi.¹,

Alaklabi.²,

Alanazi.³

et al. 2017

IJAR

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Restoration of Body Temperature to Normothermia During Resuscitation Following Trauma-Hemorrhage Improves the Depressed Cardiovascular and Hepatocellular Functions

Mizushima

Wang²,

Cioffi³

et al. 2000

Arch Surg

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Hypothesis: Rewarming the body to 37°C during resuscitation following trauma-hemorrhage has salutary effects on cardiovascular and hepatocellular functions. Design, Interventions, and Main Outcome Measures: Male rats underwent laparotomy (trauma induced) and were then bled to and maintained at a mean arterial pressure of 40 mm Hg until 40% of the maximum shed blood volume was returned in the form of Ringer lactate solution. Rats were exposed to ambient temperature and allowed to become hypothermic during hemorrhage. The animals were then resuscitated with 4 times the volume of shed blood with Ringer lactate solution for 60 minutes. In 1 group, the body temperature was rewarmed to 37°C during resuscitation. In another group, the body temperature was maintained at hypothermia (32°C) for 4 hours after resuscitation. In an additional group, the body temperature was kept at 37°C during hemorrhage and resuscitation. At 4 hours after resuscitation, the rats were returned to a room with ambient temperature. Various in vivo heart performance variables (maximal rate of pressure increase and decrease), cardiac output, hepatocellular function, and plasma IL-6 level were determined at 24 hours after resuscitation. Results: Either maintenance of normothermia during hemorrhage or prolonged hypothermia following resuscitation had deleterious effects on cardiovascular variables and hepatocellular function and up-regulated plasma IL-6 levels. In contrast, rewarming the body to 37°C during resuscitation improved cardiac contractility, cardiac output, and hepatocellular function and reduced plasma IL-6 level. Conclusion: Since rewarming the body temperature to normothermia during resuscitation improved depressed cardiovascular and hepatocellular functions, this should be considered as a useful adjunct to fluid resuscitation after trauma-hemorrhage.

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The Role of Nephrectomy in the Acutely Injured

Rotondo²,

Kauder³

et al. 2001

Arch Surg

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The high mortality in patients who undergo nephrectomy after trauma is not secondary to the nephrectomy itself but is the consequence of a more severe constellation of injuries associated with renal injuries that require operative intervention. Design: A retrospective review of all patients identified using International Classification of Diseases, Ninth Revision codes as having sustained renal injuries over a 62month period. Patients: Seventy-eight patients with renal injuries who underwent exploratory laparotomy were identified. Methods: All medical records were reviewed for patient management, definitive care, and outcome. Based on outcome, patients were assigned to either the survivor or nonsurvivor group. For patients who underwent nephrectomy, intraoperative core temperature changes, estimated blood loss, and operative time were also reviewed. Results: Seventy-eight patients with renal injuries who underwent exploratory laparotomy were identified.

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Hypothermia in Trauma Victims

Cited by 600 publications

References 0 publications

Systematic Review of Evidence-Based in Beneficial Preventing Hypothermia for Adult Trauma Patients in Accident.

Systematic Review of Evidence-Based in Beneficial Preventing Hypothermia for Adult Trauma Patients in Accident.

Restoration of Body Temperature to Normothermia During Resuscitation Following Trauma-Hemorrhage Improves the Depressed Cardiovascular and Hepatocellular Functions

The Role of Nephrectomy in the Acutely Injured

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