<i>Burkholderia</i>spp. and Related Genera

Pitt, T. L.; Dance, David A.B.

doi:10.1002/9780470688618.taw0063

Cited by 8 publications

(16 citation statements)

References 438 publications

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Section: Historical and Clinical Significance Of P Aeruginosamentioning

confidence: 99%

“…Sédillot in 1850 was first to observe that the discoloration of surgical wound dressings was associated with a transferable agent (196). The pigment responsible for the blue coloration was extracted by Fordos in 1860, and in 1862 Lucke was the first to associate this pigment with rod-shaped organisms (196). P. aeruginosa was not successfully isolated in pure culture until 1882, when Carle Gessard reported in a publication entitled "On the Blue and Green Coloration of Bandages" the growth of the organism from cutaneous wounds of two patients with bluish-green pus (65).…”

Section: Historical and Clinical Significance Of P Aeruginosamentioning

confidence: 99%

“…In the hospital, P. aeruginosa can be isolated from a variety of sources, including respiratory therapy equipment, antiseptics, soap, sinks, mops, medicines, and physiotherapy and hydrotherapy pools (199). Community reservoirs of this organism include swimming pools, whirlpools, hot tubs, contact lens solution, home humidifiers, soil and rhizosphere, and vegetables (77,196,199).…”

Section: Historical and Clinical Significance Of P Aeruginosamentioning

confidence: 99%

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Antibacterial-ResistantPseudomonas aeruginosa: Clinical Impact and Complex Regulation of Chromosomally Encoded Resistance Mechanisms

2009

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SUMMARY Treatment of infectious diseases becomes more challenging with each passing year. This is especially true for infections caused by the opportunistic pathogen Pseudomonas aeruginosa, with its ability to rapidly develop resistance to multiple classes of antibiotics. Although the import of resistance mechanisms on mobile genetic elements is always a concern, the most difficult challenge we face with P. aeruginosa is its ability to rapidly develop resistance during the course of treating an infection. The chromosomally encoded AmpC cephalosporinase, the outer membrane porin OprD, and the multidrug efflux pumps are particularly relevant to this therapeutic challenge. The discussion presented in this review highlights the clinical significance of these chromosomally encoded resistance mechanisms, as well as the complex mechanisms/pathways by which P. aeruginosa regulates their expression. Although a great deal of knowledge has been gained toward understanding the regulation of AmpC, OprD, and efflux pumps in P. aeruginosa, it is clear that we have much to learn about how this resourceful pathogen coregulates different resistance mechanisms to overcome the antibacterial challenges it faces.

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Section: Historical and Clinical Significance Of P Aeruginosamentioning

confidence: 99%

Section: Historical and Clinical Significance Of P Aeruginosamentioning

confidence: 99%

Section: Historical and Clinical Significance Of P Aeruginosamentioning

confidence: 99%

See 1 more Smart Citation

Antibacterial-ResistantPseudomonas aeruginosa: Clinical Impact and Complex Regulation of Chromosomally Encoded Resistance Mechanisms

2009

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“…Viscid, smooth and creamy colonies of B. mallei can be obtained after 48 h at 37°C (98.6°F) on these routine culture media. In the presence of nitrogen, the organism can grow as aerobic and facultative anaerobe (Pitt, 1998; OIE, 2008). On sterile potato slices, growth appears as a shiny, moist, yellowish tinged transparent film after 3 days of incubation (Davies, 1955; Naureen, 2006).…”

Section: Isolation and Identificationmentioning

confidence: 99%

“…Among laboratory animals (guinea pigs, ferrets, mice, hamsters, rabbits and monkeys), guinea pigs and hamsters are more susceptible. Cattle, fowl, rats and pigs are resistant to glanders, although the latter species is controversially discussed (Loeffler, 1886; Hu et al., 1958; Minett, 1959; OIE, 2004; Pitt and Dance, 2005). The disease appears in acute form mainly in donkeys and in its chronic form in horses.…”

Section: Epidemiologymentioning

confidence: 99%