Campylobacter jejuniisolations from Mexican and Swedish patients, with repeated symptomatic and/or asymptomatic diarrhoea episodes

Abstract

The presence of different Campylobacter jejuni serotypes in Swedish patients with diarrhoea and in Mexican patients with or without diarrhoea was investigated with special reference to repeated isolations during the course of infection and to symptomatic and asymptomatic episodes. The study included 136 C. jejuni isolates from 62 Mexican children and 173 isolates from 68 Swedish patients. The bacteria were serotyped for heat-stable (HS) and heat-labile (HL) antigen. Swedish patients, all with symptoms, were in general only infected with one serotype and were rarely reinfected. Mexican patients on the other hand were in general infected with mixed serotypes and frequently reinfected without symptoms with new, different serotypes, a finding which is in concordance with a theory of an induced immunity to surface antigens.

The serotype distribution of Campylobacter jejuni and C. coli isolated from patients with diarrhoea and controls at Tikur Anbassa Hospital, Addis Ababa, Ethiopia

“…These serogroups have commonly been associated with handling and\or consumption of chicken and cattle [14,19,27]. From this study, as in a former one [13], we also found that children in developing countries frequently carry more than one campylobacter strain at one occasion. From approximately 20 % of the cases more than one strain could be identified, both in regard to the species identification as well as to the serotyping [25].…”

“…Major questions in investigations of campylobacter hitherto have been directed towards understanding the sources of campylobacter infection as well as the mode of transmission of the bacteria. Poultry appears to be a significant source of campylobacter [13,18,19]. Different serotyping systems have been developed to provide additional markers in the study of the epidemiological features of these organisms [4][5][6][7][20][21][22].…”

“…These were detected using the indirect haemagglutination technique as described by Penner and colleagues [6], with a heated supernatant from the bacterial culture as antigen. The polyclonal HS antisera used were 1, 2, 3, 4, 5 : 1 (C. jejuni), 5 : 2 (C. coli), 6,7,8,9,10,11,13,14,15,16,17,18,20,24,26,27,28,30,31,34,37,39,46,48,49,51,56 and 59 which had earlier been shown to give a typability of 75 % for C. jejuni\coli strains from Swedish patients. The corresponding antigens are common in Canada [6].…”

“…Since the recognition of campylobacter as one of the commonest causes of bacterial diarrhoea in humans [1][2][3], different typing systems such as serotyping [4][5][6], biotyping [7,8], phage-typing as well as different genotypic methods [9,11] have been proposed for improving the understanding of the epidemiological features of campylobacter diseases. The serotype distribution from different parts of the world [12][13][14][15] has been investigated using the Lior [4] and the Penner [5] system but not hitherto from Ethiopia. The aim of the present work was to study the frequency of different serotypes among campylobacter isolated children (less than 15 years of age).…”

Enhancement of Disease and Pathology by Synergy of Trichuris Suis and Campylobacter Jejuni in the Colon of Immunologically Naive Swine

“…14 In another study, there was no difference in serotypes isolated from symptomatic and asymptomatic children. 15 The main explanation for the different disease expression in developing versus developed countries has been the early acquisition of immunity by children exposed to hyperendemic and/or polymicrobial infection. 16−18 There is documentation of concurrent infections precipitating C. jejuni enteritis.…”