<i>Candida albicans</i>Endocarditis Associated with a Contaminated Aortic Valve Allograft: Implications for Regulation of Allograft Processing

Kuehnert, Matthew J.; Clark, Elizabeth; Lockhart, Shawn R.; Soll, David R.; Chia, John Whay Kuang; Jarvis, William R.

doi:10.1086/514944

Cited by 51 publications

(24 citation statements)

References 10 publications

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“…Furthermore, DNA fingerprinting with Ca3 fulfills the general requirements set forth in a previous section of this review for effective fingerprinting methods (288). Ca3 and 27A have been used in a number of epidemiological studies of C. albicans and the highly related species C. dubliniensis (see, e.g., references 6,80,137,164,168,192,196,216,218,227,246,265,FIG. 4.…”

Section: Restriction Fragment Length Polymorphisms With Hybridizationmentioning

confidence: 99%

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The Ins and Outs of DNA Fingerprinting the Infectious Fungi

Soll

2000

Clinical Microbiology Reviews

283

317

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Section: Restriction Fragment Length Polymorphisms With Hybridizationmentioning

confidence: 99%

“…Since the banding pattern generated by the C. albicans DNA fingerprinting probe Ca3 (Fig. 6A) has received intense scrutiny using computerassisted systems (137,164,168,192,196,268,329,330,332,336,358), it will be used as a model to describe how complex banding patterns can be analyzed.…”

Section: Analysis Of Complex Banding Patternsmentioning

confidence: 99%

The Ins and Outs of DNA Fingerprinting the Infectious Fungi

Soll

2000

Clinical Microbiology Reviews

283

317

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“…13 Apart from bacterial infections, allograft-related virus and fungal infections have also been reported. [14][15][16] The TB infection after allogenic grafts was seen especially after bone and heart valve grafting. 12 Considering the CNS, fatal complications such as prion diseases (Creutzfeldt-Jakob disease) have been reported after allogenic dural grafting 11 but there have been no reports citing allogenic dural graft-related TB in the CNS.…”

Section: Discussionmentioning

confidence: 99%

Central Nervous System Tuberculosis Subsequent to Dural Grafting

Sanuş

Tanrıverdi

Tutunculer

et al. 2008

Can. j. neurol. sci.

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Despite modern diagnostic and treatment modalities, tuberculosis (TB) still remains a major worldwide health problem. Resurgence in developed countries is due mainly to infection with the human immunodeficiency virus, immigration from developing and/or underdeveloped countries, transmissions in hospitals and prisons and development of multidrug-resistant strains of TB.1 According to the estimates of World Health Organization, TB accounts for 7-8 million new cases every year and is responsible for 2.9 million deaths worldwide annually. 2Tuberculosis infection is encountered mainly in underdeveloped or developing countries, but increasing infection rate has recently been reported even in developed countries.3 As a developing country, it has been estimated that TB is increasing rather than decreasing since the 1970s in Turkey and is still a serious problem in this country. 4 It has been estimated that neurological involvement of TB infection constitutes approximately 5-15 % of the cases, with a high predominance in children. 5,6 Central nervous system (CNS) involvement including atypical forms have been reported and reviewed extensively in the literature. [7][8][9] The bacteria are transmitted through inhalation of aerosolized droplets and CNS involvement occurs mainly by hematogenous route. Although iatrogenic CNS infections have been reported, such as after lumbar puncture, 10 there has been no report of CNS TB after allogenic dural grafting.This report concerns allogenic dura mater graft-related lumbar and cerebellar TB in a 20-year old male who underwent on operation to correct Chiari type-I malformation in which posterior fossa decompression followed by allograft dural grafting had been performed. As far as we know, this is the first report of CNS TB following the use of allograft dura mater. CASE REPORTA 20-year-old male was referred to the Neurosurgical Department, Cerrahpasa Medical Faculty, Istanbul University, for further diagnosis and treatment. The patient complained of lumbar pain radiating to both lower extremities, which was accompanied by recent headache. Physical examination disclosed nothing abnormal. However, neurological examination revealed lower extremity weakness (1/5) and neck stiffness. Medical history showed that he had an operation to correct a Chiari type-I malformation, in which posterior decompression plus C1 laminectomy and dural grafting with cadaveric allograft was performed six months prior to the admission to us ( Figure 1) PEER REVIEWED LETTERsevere headache and neck pain four months after the surgical intervention. He was evaluated by his primary neurosurgeon and radiological examination at that time disclosed the syrinx had resolved completely and so it was decided to follow the patient clinically. Two months after his last visit, he developed severe

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“…While less commonly identified, infections in tissue and eye allografts have also been reported. Tissue transplants associated with transmission of various infections in the US include Candida albicans (Kuehnert et al 1998), Clostridium sordellii (Kainer et al 2004), HCV (Tugwell et al 2005), Epstein-Barr virus (Larsen et al 2007), group A Streptococcus (Lee et al 2007), clostridial endophthalmitis (JAMA 2005), and Chryseobacterium meningosepticum (now Elizabethkingia meningoseptica) (Srinivasan et al, in preparation). In the use of eye tissues, data from 1991 to 2005 showed that primary graft failures (PGFs), endophthalmitis (bacterial and fungal), keratitis, corneal dystrophy/degeneration, and scleral graft rejection were the most common adverse reactions (Hassan et al 2008).…”

Section: Recent Outbreaks Associated With Allograft Transplantationmentioning

confidence: 99%

Organ and tissue safety workshop 2007: advances and challenges

2008

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A workshop in June 2005 ("Preventing Organ and Tissue Allograft-Transmitted Infection: Priorities for Public Health Intervention") identified gaps in organ and tissue safety in the US. Participants developed a series of allograft safety initiatives. "The Organ and Tissue Safety Workshop 2007: Advances and Challenges" assessed progress and identified priorities for future interventions. Awareness of the challenges of allograft-associated disease transmission has increased. The Transplantation Transmission Sentinel Network will enhance communication surrounding allograft-associated disease transmission. Other patient safety initiatives have focused on adverse event reporting and microbiologic screening technologies. Despite progress, improved recognition and prevention of donor-derived transmission events is needed. This requires systems integration across the organ and tissue transplantation communities including organ procurement organizations, eye and tissue banks, and transplant infectious disease experts. Commitment of resources and improved coordination of efforts are required to develop essential tools to enhance safety for allograft recipients.

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Candida albicansEndocarditis Associated with a Contaminated Aortic Valve Allograft: Implications for Regulation of Allograft Processing

Cited by 51 publications

References 10 publications

The Ins and Outs of DNA Fingerprinting the Infectious Fungi

The Ins and Outs of DNA Fingerprinting the Infectious Fungi

Central Nervous System Tuberculosis Subsequent to Dural Grafting

Organ and tissue safety workshop 2007: advances and challenges

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