Chryseobacterium gleum – a novel bacterium species detected in neonatal respiratory tract infections

Abstract

We report three patients with early neonatal infections. All patients had respiratory tract involvement with increased inflammation markers. Chryseobacterium gleum was cultured from the stomach content aspirated on arrival at the Neonatal intensive Care Unit and it was identified with the help of a Microflex™ MALDI Biotyper mass spectrometer (Bruker-Daltonik, Fremont, CA). Recovery could be achieved with ciprofloxacin treatment. We consider our cases a possible new clinical presentation of a rare human pathogen.

Chryseobacterium gleum in a man with prostatectomy in Senegal: a case report and review of the literature

“…C. gleum is an unusual human pathogen that has been reported as the cause of early neonatal respiratory infection in three neonates [3]. The most common species causing human disease is F. meningosepticum followed by C. indologenes and C. gleum [10].…”

“…Chryseobacterium is typically found in soil, water, plants, and food products and can survive in hospital environments, chlorinated water, and wet surfaces, all of which serve as potential reservoirs of infection. A literature search revealed only a few published cases in countries including Hungary, India, Croatia, and Saudi Arabia [3–6]. In Senegal, two cases of meningitis due to Flavobacterium meningosepticum were diagnosed in the late 1970s [7] as well as one case of Chryseobacterium indologenes [8].…”

Ritkábban előforduló, alsó légúti fertőzést okozó Gram-negatív nem fermentáló pálcák

“…Leggyakrabban a C. gleum és C. indologenes fajok fordultak elő az elemzett mintákban. Érdemes megjegyezni, hogy a C. gleumot újszülöttek alsó légúti fertőzéseiben is leírták kórokozóként [11]. Esetleírásban számoltak már be COPD-s beteg kórházi előzmény nélküli C. indologenes-pneumoniájáról [12].…”

Sepsis Due to <i>Chryseobacterium gleum</i> in a Diabetic Patient with Chronic Obstructive Pulmonary Disease: a Case Report and Mini Review

“…Patients at both extremes of age and immunocompromised individuals are more susceptible to this infection (6,7). Very limited clinical data are available for this newly identified pathogen, and it has been rarely reported as a cause of sepsis anywhere in the world (Table 1) (8).…”

“…Most of the cases of C. gleum infections have been treated successfully with a fluoroquinolone (ciprofloxacin and levofloxacin) or piperacillin-tazobactam (1,6,7). In contrast, Garg et al reported resistance to fluoroquinolones and susceptibility to only tetracycline and minocycline (9).…”