<i>Fagopyrum tataricum</i> ethanol extract ameliorates symptoms of hyperglycemia by regulating gut microbiota in type 2 diabetes mellitus mice

Ge, Xiaodong; Liu, Tingting; Chen, Zhuo; Zhang, Jiawei; Yin, Xuemei; Huang, Zirui; Chen, Ligen; Zhao, Chao; Shao, Rong; Xu, Wei

doi:10.1039/d3fo02385k

Food Funct.

2023

DOI: 10.1039/d3fo02385k

|View full text |Cite

Fagopyrum tataricum ethanol extract ameliorates symptoms of hyperglycemia by regulating gut microbiota in type 2 diabetes mellitus mice

Xiaodong Ge,

Tingting Liu,

Zhuo Chen

et al.

Abstract: FTE ameliorates symptoms of hyperglycemia by regulating gut microbiota in T2DM mice.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

2025

Publication Types

Select...

Article5

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 5 publications

References 58 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Antidiabetic and hypolipidemic activities of Sanghuangporus vaninii compounds in streptozotocin‐induced diabetic mice via modulation of intestinal microbiota

Huang,

Chen,

et al. 2024

eFood

View full text Add to dashboard Cite

Sanghuangporus vaninii is a traditional edible and medicinal fungi with a long history in China. Recent studies have focused on its potential in treating diabetes, although the underlying mechanism remains unclear. This study aimed to investigate the antidiabetic and hypolipidemic effects of the formula of S. vaninii compounds (SVC) in diabetic mice and explore the potential improvement in the intestinal microbiota. Oral administration of SVC significantly reduced fasting blood glucose and improved insulin sensitivity and lipid indexes. In addition to its direct effects on glucose levels and insulin sensitivity, SVC was found to have an impact on the intestinal microbiota. The levels of short‐chain fatty acids receiving SVC intervention increased, and 16S rRNA sequencing revealed changes in the abundances of certain bacteria, such as Harryflintia, Helicobacter, Candidatus_Soleaferrea, Klebsiella, and Candidatus_Stoquefichus. These bacteria were found to be negatively associated with glucose and lipid indexes and positively related to body weight and insulin sensitivity. Overall, this study highlights the potential of SVC in treating diabetes and provides a novel perspective for understanding its antidiabetic mechanism through modulation of the intestinal microbiota.

show abstract

Antidiabetic and hypolipidemic activities of Sanghuangporus vaninii compounds in streptozotocin‐induced diabetic mice via modulation of intestinal microbiota

Huang,

Chen,

et al. 2024

eFood

View full text Add to dashboard Cite

show abstract

(−)-Epicatechin ameliorates type 2 diabetes mellitus by reshaping the gut microbiota and Gut–Liver axis in GK rats

Zeng,

Liu,

Wan

et al. 2024

Food Chemistry

View full text Add to dashboard Cite

Oral sericin ameliorates type 2 diabetes through passive intestinal and bypass transport into the systemic circulation

Zhang,

Wang,

Zhong

et al. 2024

Journal of Ethnopharmacology

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Fagopyrum tataricum ethanol extract ameliorates symptoms of hyperglycemia by regulating gut microbiota in type 2 diabetes mellitus mice

Abstract: FTE ameliorates symptoms of hyperglycemia by regulating gut microbiota in T2DM mice.

Cited by 5 publications

References 58 publications

Antidiabetic and hypolipidemic activities of Sanghuangporus vaninii compounds in streptozotocin‐induced diabetic mice via modulation of intestinal microbiota

Antidiabetic and hypolipidemic activities of Sanghuangporus vaninii compounds in streptozotocin‐induced diabetic mice via modulation of intestinal microbiota

(−)-Epicatechin ameliorates type 2 diabetes mellitus by reshaping the gut microbiota and Gut–Liver axis in GK rats

Oral sericin ameliorates type 2 diabetes through passive intestinal and bypass transport into the systemic circulation

Contact Info

Product

Resources

About