Helicobacter spp. Other than <scp>H</scp>. pylori

Rossi, Mirko; Hänninen, Marja‐Liisa

doi:10.1111/j.1523-5378.2012.00984.x

Cited by 16 publications

(12 citation statements)

References 47 publications

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“…Recent studies focused on the association between non- H. pylori Helicobacter species (NHPH) and human gastrointestinal diseases, including Crohn’s disease, hepatobiliary disease, and gastritis [ 68 , 69 , 70 ]. Entero-hepatic Helicobacteraceae were detected by PCR sequencing in 59% of fecal samples from children with Crohn’s disease, compared to 9% in healthy controls [ 69 ].…”

Section: Inflammatory Bowel Diseases and Helicobacter mentioning

confidence: 99%

Metabolic Interaction of Helicobacter pylori Infection and Gut Microbiota

Yang

Sheu

2016

Microorganisms

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As a barrier, gut commensal microbiota can protect against potential pathogenic microbes in the gastrointestinal tract. Crosstalk between gut microbes and immune cells promotes human intestinal homeostasis. Dysbiosis of gut microbiota has been implicated in the development of many human metabolic disorders like obesity, hepatic steatohepatitis, and insulin resistance in type 2 diabetes (T2D). Certain microbes, such as butyrate-producing bacteria, are lower in T2D patients. The transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome, but the exact pathogenesis remains unclear. H. pylori in the human stomach cause chronic gastritis, peptic ulcers, and gastric cancers. H. pylori infection also induces insulin resistance and has been defined as a predisposing factor to T2D development. Gastric and fecal microbiota may have been changed in H. pylori-infected persons and mice to promote gastric inflammation and specific diseases. However, the interaction of H. pylori and gut microbiota in regulating host metabolism also remains unknown. Further studies aim to identify the H. pylori-microbiota-host metabolism axis and to test if H. pylori eradication or modification of gut microbiota can improve the control of human metabolic disorders.

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Section: Inflammatory Bowel Diseases and Helicobacter mentioning

confidence: 99%

Metabolic Interaction of Helicobacter pylori Infection and Gut Microbiota

Yang

Sheu

2016

Microorganisms

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“…The most studied GH species so far is Helicobacter pylori , being considered the main cause of gastritis and peptic ulcer in humans and has been determined to be an important risk factor in the development of gastric adenocarcinoma and lymphoma of lymphoid tissue associated with mucosa (MALT) (Baele et al, ). However, during the last few years EHH species have become increasingly important as emerging pathogens and potential zoonotic agents (Collado et al, ), demonstrating their association with several human diseases like acute gastroenteritis, inflammatory bowel disease and hepatobiliary diseases (Solnick and Schauer, ; Smet et al, ; Rossi and Hänninnen, ). Unfortunately, there is no specific isolation protocol for these species, but occasionally, they are isolated using culture medium and atmospheric conditions designed for the taxonomic close related genus Campylobacter .…”

Section: Introductionmentioning

confidence: 99%

Comparison of media and growth conditions for culturing enterohepaticHelicobacterspecies

Ochoa

Martínez

Fernández

et al. 2019

Lett Appl Microbiol

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This research aims to compare the culturing conditions for enterohepatic Helicobacter, evaluating culture media, incubation atmosphere and susceptibility to antimicrobials used to generate selective conditions. Four common media for the closely related genus Campylobacter (Columbia, Bolton, Brucella and CCDA agar), as well as the need for hydrogen in the microaerobic incubation atmosphere, were evaluated. Serial dilutions of 13 strains belonging to six species (H. apodemus, H. bilis, H. canicola, H. canis, H. equorum and Helicobacter sp.) were inoculated in each media and incubated at 37°C for 48 to 96 h using CampyGen (OXOID) and gaseous exchange (including hydrogen) in parallel. Columbia or Brucella agars were the most appropriate for culturing EHH (P < 0·05). However, there was no significant difference between the atmospheres evaluated (P = 0·13). In addition, minimal inhibitory concentration for six antibiotics showed that all isolates were resistant to trimethoprim, whereas for the rest of the antibiotics (cephalothin, cefoperazone, cefsulodin, teicoplanin and vancomycin) the inhibition range was between 8 and 64 μg ml−1. Our findings suggest that Columbia or Brucella media, regardless of the use of hydrogen, can be used for the EHH isolation. In addition, the concentration of antibiotics included in commercial campylobacteria supplements is suitable for EHH species recovery. Significance and Impact of the Study Enterohepatic Helicobacter (EHH) infections have been associated with several diseases in humans such as acute gastroenteritis, inflammatory bowel disease and hepatobiliary diseases. Although they are frequently detected in clinical samples by molecular methods, only occasionally they are isolated using culture conditions described for the taxonomic related pathogen Campylobacter sp. This is because the optimal conditions for the isolation of EHH have not yet been described, which results in an underestimation of the prevalence and clinical importance of these emerging pathogens. Therefore, this study provides insight for culturing EHH species.

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“…La presencia e importancia de otras especies de Helicobacter también es controversial, pero hay estudios que apuntan a una relación de las mismas con diferentes padecimientos como cáncer, litiasis biliar y enfermedades cardiacas 161,162 . Es interesante notar que H. pylori, y probablemente otras especies microbianas, tiene la capacidad de migrar a diferentes secciones dentro del estómago 163 , lo cual podría repercutir en los hallazgos y conclusiones reportadas entre los diferentes estudios.…”

Section: Patologías Asociadas a La Infección Por Helicobacter Pyloriunclassified