<i>Helicobacter Pylori: A</i> Possible Association with Otitis Media with Effusion

Yılmaz, Taner; Ceylan, Seyit Mehmet; Akyön, Yakut; Özçakýr, Olcay; Gürsel, Bülent

doi:10.1016/j.otohns.2006.02.002

Cited by 56 publications

(64 citation statements)

References 16 publications

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“…It is known to be present in the oropharyngeal area in subgingival plaques, dental plaques and saliva (1). In recent years, research has shown its presence in middle ear effusions and tonsil and adenoid tissues (8,9).…”

Section: Discussionmentioning

confidence: 99%

Relationship between Helicobacter pylori Adenotonsillar Colonization and Frequency of Adenotonsillitis in Children

et al. 2013

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Section: Discussionmentioning

confidence: 99%

Relationship between Helicobacter pylori Adenotonsillar Colonization and Frequency of Adenotonsillitis in Children

et al. 2013

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“…Yılmaz et al [6] evaluated 22 children with OME (patient group) and 20 children who underwent surgery for other conditions (control group). They identified H. pylori in both the tonsil and adenoid samples by PCR and CLO methods.…”

Section: Correlation Among Pepsinogen Levels In Middle Ear Fluid and mentioning

confidence: 99%

“…The main question is whether the acidic pH and the presence of pepsin or the toxic effect of the presence of refluxed H. pylori is responsible for the pathological process. Yılmaz et al [6] investigated this issue by prescribing antibiotic and acid suppression therapy for H. pylori eradication. Amoxicillin and clarithromycin are used to eradicate H. pylori.…”

Section: Correlation Among Pepsinogen Levels In Middle Ear Fluid and mentioning

confidence: 99%

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Role of Laryngopharyngeal Reflux in the Pathogenesis of Otitis Media with Effusion

Doğru

Kuran²,

Haytoğlu³

et al. 2015

Int Adv Otol

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OBJECTIVE:To determine whether there is an association between otitis media with effusion and laryngopharyngeal reflux in children. MATERIALS and METHODS:This study included 31 children with otitis media with effusion. The pepsinogen level in the middle ear fluid of all patients was measured by sandwich enzyme-linked immunosorbent assay. Each patient's middle ear fluid was investigated for Helicobacter pylori (H. pylori) using the Campylobacter-like organism (CLO) test. The middle ear pepsinogen levels were compared with those in the serum. The correlation between pepsinogen levels and H. pylori positivity in the middle ear fluid was investigated. RESULTS:The mean middle ear pepsinogen level (211.69 ng/mL) was significantly higher than that in the serum (24.18 ng/mL) in patients with otitis media with effusion. The middle ear aspirates of six patients (19%) were positive for H. pylori, and the correlation between H. pylori positivity and increased pepsinogen levels in the middle ear fluid was statistically significant in patients with otitis media with effusion. CONCLUSION:We detected higher pepsinogen levels and H. pylori positivity rates in the middle ear fluid than in the serum of patients with otitis media with effusion. These results support the role of laryngopharyngeal reflux in the pathogenesis of otitis media with effusion.

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“…Yilmaz et al (2004) found H. pylori in middle ear effusions and in one adenoid tissue specimen using PCR (23S rRNA gene). Yilmaz et al (2006) found H. pylori in 64% of adenoid and tonsillar specimens by PCR (16S rRNA gene). Kusano et al (2007) showed H. pylori positivity in 126 (72.9%) tonsillar specimens using PCR (16S rRNA gene).…”

Section: H Pylori In Oropharyngeal Lymphatic Tissuementioning

confidence: 99%