<i>Helicobacter pylori</i> and rosacea

Rebora, Alfredo

doi:10.1046/j.1468-3083.2000.00132.x

Cited by 46 publications

(60 citation statements)

References 2 publications

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“…Moreover, it is typical that rosacea presents with a seasonal periodicity like peptic ulcer disease (4), and likewise it has been known for years that some antibiotics used in the eradication, as clarithromycin and metronidazole (24), can be useful to a certain extent in the management of some rosacea patients. In 1994, Rebora et al (25) described the association between H. pylori and rosacea. Since then, several studies have shown an elevated prevalence of H. pylori infection in patients with rosacea (15,(26)(27)(28), even when compared with age-and sex-matched control patients (29).…”

Section: Resultsmentioning

confidence: 99%

Effect of Helicobacter pylori eradication therapy in rosacea patients

Miquel

Romero

Sequeiros

et al. 2006

Rev. esp. enferm. dig.

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Objective: the causal relation between rosacea and Helicobacter pylori infection is discussed. We evaluated the clinical evolution of rosacea after infection eradication.Patients and methods: we have prospectively studied 44 patients diagnosed with rosacea. Helicobacter pylori infection was determined, and infected patients were treated with eradication therapy. The evolution of dermatological symptoms in a subgroup of 29 infected patients in whom eradication had been achieved was followed during 16.8 (± 17.8) months. Median age was 50.6 (± 14.1) years for 22 women (75.9%) and 7 men (24.1%). Clinical response according to gender and clinical subtype of rosacea was evaluated.Results: complete improvement was observed in 10 patients (34.5%; 95% CI: 18.6-54.3%), relevant improvement in 9 (31.1%; 95% CI: 16-51%), poor improvement in 5 (17.2%; 95% CI: 6.5-36.4%), and absence of improvement in 5 cases (17.2%; 95% CI: 6.5-36.4%). No significant differences in dermatological evolution according to sex were observed. Regarding subtype of rosacea there was a relevant improvement in 83.3% (95% CI: 64.1-93.8%) of cases with papulopustular type as opposed to 36.5% (95% CI: 20-56.1%) of cases with erythematous predominance, p = 0.02.Conclusions: based on these results, the relation between Helicobacter pylori and rosacea is supported, and infection should be investigated in these patients because an appreciable percentage of patients diagnosed with rosacea and Helicobacter pylori infection can benefit from eradication therapy, mainly in the papulopustular subtype.

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Section: Resultsmentioning

confidence: 99%

Effect of Helicobacter pylori eradication therapy in rosacea patients

Miquel

Romero

Sequeiros

et al. 2006

Rev. esp. enferm. dig.

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“…H. pylori infection is one of the most common bacterial diseases world-wide. A high H. pylori seroprevalence has also been found in many extragastrointestinal disorders, including coronary heart disease , rosacea (Rebora et al 1994), growth failure in childhood (Patel et al 1994), active bronchiectasis (Tang et al 1998) and chronic obstructive pulmonary disease (COPD) (Roussos et al 2005). Recently, H. pylori has been identified in the tracheobronchial aspirates in mechanically ventilated patients, suggesting that it might cause ventilator-associated pneumonia (Mitz and Farber 1993).…”

confidence: 99%

Helicobacter pylori Seroprevalence in Patients with Mild Asthma

Zhao

Yang

Shimizu

et al. 2005

Tohoku J. Exp. Med.

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“…pylori infection is a major public health problem as it is widespread and frequent (Simsek et al 2000). A high H. pylori seroprevalence has also been found in many extragastrointestinal disorders, including coronary heart disease , rosacea (Rebora et al 1994), growth failure in childhood (Patel et al 1994) and active bronchiectasis (Tsang et al 1998). Recently, H. pylori have been identified in the tracheobronchial aspirates in mechanically ventilated patients and the possibility that it might cause ventilatorassociated pneumonia has been raised (Mitz and Farber 1993), it appears that H. pylori has a close relationship with respiratory diseases (Jun et al 2005).…”

confidence: 99%