<i>In situ</i> Evolution of the Mechanical Properties of Stretchable and Non-Stretchable ePTFE Vascular Grafts and Adjacent Native Vessels

Famaey, Nele; Verhoeven, Jelle; Jacobs, Steven; Pettinari, Matteo; Meyns, Bart

doi:10.5301/ijao.5000368

Cited by 12 publications

(5 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Famaey et al [6] compared stretchable and non-stretchable expanded PTFE by axial tension and found a strength of 41.48±3.34 MPa for stretchable expanded PTFE and 32.40±3.80 MPa for non-stretchable expanded PTFE. However, they used a rectangular test sample (10×5 mm) for the axial tension test.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Biomechanical Properties of Dura Mater Substitutes and Cranial Human Dura Mater : An In Vitro Study

Kızmazoğlu

Aydın²,

Kaya³

et al. 2019

J Korean Neurosurg Soc

View full text Add to dashboard Cite

ObjectiveThe aim of this study was to investigate the biomechanical differences between human dura mater and dura mater substitutes to optimize biomimetic materials. MethodsFour groups were investigated. Group I used cranial dura mater (n=10), group II used Gore-Tex® Expanded Cardiovascular Patch (W.L. Gore & Associates Inc., Flagstaff, AZ, USA) (n=6), group III used Durepair® (Medtronic Inc., Goleta, CA, USA) (n=6), and group IV used Tutopatch® (Tutogen Medical GmbH, Neunkirchen am Brand, Germany) (n=6). We used an axial compression machine to measure maximum tensile strength. ResultsThe mean tensile strengths were 7.01±0.77 MPa for group I, 22.03±0.60 MPa for group II, 19.59±0.65 MPa for group III, and 3.51±0.63 MPa for group IV. The materials in groups II and III were stronger than those in group I. However, the materials in group IV were weaker than those in group I. ConclusionAn important dura mater graft property is biomechanical similarity to cranial human dura mater. This biomechanical study contributed to the future development of artificial dura mater substitutes with biomechanical properties similar to those of human dura mater.

show abstract

Section: Discussionmentioning

confidence: 99%

Comparison of Biomechanical Properties of Dura Mater Substitutes and Cranial Human Dura Mater : An In Vitro Study

Kızmazoğlu

Aydın²,

Kaya³

et al. 2019

J Korean Neurosurg Soc

View full text Add to dashboard Cite

show abstract

“…This was because the fibers with high order had a lower tangle degree between the fibers than that of the knotted random fibers. According to the literature, the stress range of the human aorta is .2–1.6 MPa ( Famaey et al, 2014 ; Backman et al, 2017 ; Maleki and Kalantarnia, 2022 ). The stresses of the fiber membranes were much higher than the stress requirements of the human aorta, indicating that they met the mechanical strength requirements for implantation in the body.…”

Section: Resultsmentioning

confidence: 99%

Preparation and performance of random- and oriented-fiber membranes with core–shell structures via coaxial electrospinning

Jin²,

Fan³

et al. 2023

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

The cells and tissue in the human body are orderly and directionally arranged, and constructing an ideal biomimetic extracellular matrix is still a major problem to be solved in tissue engineering. In the field of the bioresorbable vascular grafts, the long-term functional prognosis requires that cells first migrate and grow along the physiological arrangement direction of the vessel itself. Moreover, the graft is required to promote the formation of neointima and the development of the vessel walls while ensuring that the whole repair process does not form a thrombus. In this study, poly (l-lactide-co-ε-caprolactone) (PLCL) shell layers and polyethylene oxide (PEO) core layers with different microstructures and loaded with sodium tanshinone IIA sulfonate (STS) were prepared by coaxial electrospinning. The mechanical properties proved that the fiber membranes had good mechanical support, higher than that of the human aorta, as well as great suture retention strengths. The hydrophilicity of the oriented-fiber membranes was greatly improved compared with that of the random-fiber membranes. Furthermore, we investigated the biocompatibility and hemocompatibility of different functional fiber membranes, and the results showed that the oriented-fiber membranes containing sodium tanshinone IIA sulfonate had an excellent antiplatelet adhesion effect compared to other fiber membranes. Cytological analysis confirmed that the functional fiber membranes were non-cytotoxic and had significant cell proliferation capacities. The oriented-fiber membranes induced cell growth along the orientation direction. Degradation tests showed that the pH variation range had little change, the material mass was gradually reduced, and the fiber morphology was slowly destroyed. Thus, results indicated the degradation rate of the oriented-fiber graft likely is suitable for the process of new tissue regeneration, while the random-fiber graft with a low degradation rate may cause the material to reside in the tissue for too long, which would impede new tissue reconstitution. In summary, the oriented-functional-fiber membranes possessing core–shell structures with sodium tanshinone IIA sulfonate/polyethylene oxide loading could be used as tissue engineering materials for applications such as vascular grafts with good prospects, and their clinical application potential will be further explored in future research.

show abstract

“…Zerris et al [27] reported that the mean tensile strength of Durepair ® (bovine collagen dural graft; Medtronic, Minneapolis, MN, USA) was 22.70±2.83 MPa. Famaey et al [3] compared the axial tension in stretchable and non-stretchable expanded polytetraf luoroethylene and reported values of 41.48±3.34 MPa and 32.40±3.80 MPa for stretchable and non-stretchable, respectively. These studies explained that artificial dura mater substitutes were more durable than native human cranial dura mater.…”

Section: Discussionmentioning

confidence: 99%

Biomechanical Properties of the Cranial Dura Mater with Puncture Defects : An In Vitro Study

Aydın¹,

Kızmazoğlu

Kaya³

et al. 2019

J Korean Neurosurg Soc

View full text Add to dashboard Cite

Objective The primary aim of this investigation was to explore the nature of dura mater biomechanics following the introduction of puncture defect(s). Methods Twenty-eight dura mater specimens were collected during autopsy from the department of forensic medicine of the authors' institution. Specimens were divided randomly into one of four groups : group I (cranial dura mater; n=7), group II (cranial dura mater with one puncture defect; n=7); group III (cranial dura mater with two puncture defects; n=7), and group IV (cranial dura mater with three puncture defects; n=7). Results The mean±standard deviation tensile strengths of the dura mater were 8.35±3.16, 8.22±3.32, 7.13±1.77, and 6.94±1.93 MPa for groups I, II, III, and IV, respectively. There was no statistical difference between all groups. A single, two or more punctures of the dura mater using a 20-gauge Quincke needle did not affect cranial dura tensile strength. Conclusion This biomechanical study may contribute to the future development of artificial dura mater substitutes and medical needles that have a lower negative impact on the biomechanical properties of dura mater.

show abstract

In situ Evolution of the Mechanical Properties of Stretchable and Non-Stretchable ePTFE Vascular Grafts and Adjacent Native Vessels

Cited by 12 publications

References 18 publications

Comparison of Biomechanical Properties of Dura Mater Substitutes and Cranial Human Dura Mater : An In Vitro Study

Comparison of Biomechanical Properties of Dura Mater Substitutes and Cranial Human Dura Mater : An In Vitro Study

Preparation and performance of random- and oriented-fiber membranes with core–shell structures via coaxial electrospinning

Biomechanical Properties of the Cranial Dura Mater with Puncture Defects : An In Vitro Study

Contact Info

Product

Resources

About