2010
DOI: 10.3109/08923970903143957
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In vitrostudies on the relationship between the anti-inflammatory activity ofPhysalis peruvianaextracts and the phagocytic process

Abstract: The study of plants used in traditional medicine has drawn the attention of researchers as an alternative in the development of new therapeutics agents, such as the American Solanaceae Physalis peruviana, which has significant anti-inflammatory activity. The Physalis peruviana anti-inflammatory effect of ethanol or ether calyces extracts on the phagocytic process was assessed by using an in vitro phagocytosis model (Leishmania panamensis infection to murine macrophages). The Physalis peruviana extracts do not … Show more

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Cited by 23 publications
(10 citation statements)
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“…60 Similarly, J774 murine macrophages infected with Leishmania that were treated with ethanol extract from Physalis peruviana calyxes showed decreased expression in IL-6 and MCP-1. 24 In general, a strong anti-inflammatory effect has been shown in analyzed extracts from Physalis peruviana fruits. The efficacy of those products depends on the tumor model and compound or compounds being analyzed, an aspect that requires further research.…”
Section: Cytokines Expressionmentioning
confidence: 99%
“…60 Similarly, J774 murine macrophages infected with Leishmania that were treated with ethanol extract from Physalis peruviana calyxes showed decreased expression in IL-6 and MCP-1. 24 In general, a strong anti-inflammatory effect has been shown in analyzed extracts from Physalis peruviana fruits. The efficacy of those products depends on the tumor model and compound or compounds being analyzed, an aspect that requires further research.…”
Section: Cytokines Expressionmentioning
confidence: 99%
“…Physalis peruviana , commonly known as cape gooseberry, is a solanaceous plant native to tropical South America, typically growing in the Andes at 2000 m. Its economic value has grown in the last three decades as a result in part of its nutritional and medicinal properties (Franco et al., ; Martinez et al., ; Ramadan, ). Cape gooseberry represents the second most important fruit export in Colombia, worth approximately US$30 million per annum (Barrero et al., ).…”
Section: Introductionmentioning
confidence: 99%
“…In this sense, Physalis peruviana L. (Solanaceae), widely used in traditional medicine as a diuretic and hypoglycemic agent and to treat malaria, asthma, hepatitis, dermatitis, and rheumatoid arthritis [10], represents a promissory source of bioactive compounds. This has been experimentally validated, with extracts showing relevant antioxidant [11,12], antiproliferative [13][14][15], cytotoxic [16], anti-hepatotoxic [17], hipoglycaemic [18], immunomodulatory [19], and anti-inflammatory activities [20,21]. P. peruviana, also known as "uchuva" in Colombia or "gooseberry" in English speaking countries, is native to tropical South America and is characterized because the fruit grows enclosed in a papery husk or calyx, which is one of the best-known examples of persistent sepals due to its conspicuous post-floral growth and enlargement [22][23][24].…”
mentioning
confidence: 99%