<i>Kampo</i> in Women's Health: Japan's Traditional Approach to Premenstrual Symptoms

Gepshtein, Yana; Plotnikoff, Gregory A.; Watanabe, Kenji

doi:10.1089/acm.2007.7064

Cited by 12 publications

(10 citation statements)

References 29 publications

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“…For the treatment of hie as a disease entity, prescriptions covered by the health insurance include shimotsu-to , keishi-bukuryogan , goshakusan , and kami-shoyosan [12]. This study aimed to educate nonspecialized physicians in Kampo medicine on the importance of treating hie and to increase awareness of the utility of Kampo medicine in such treatments.…”

Section: Introductionmentioning

confidence: 99%

Clinical Data Mining Related to the Japanese Kampo Concept “Hie” (Oversensitivity to Coldness) in Men and Pre‐ and Postmenopausal Women

Tokunaga

Munakata

Katayama

et al. 2014

Evidence-Based Complementary and Alternative Medicine

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“Hie” is a subjective oversensitivity to cold and a condition experienced in 60% of Japanese citizens. The condition of hie has not been documented in Western medicine. However, in Kampo medicine, hie is an important target of treatment, because it has been considered one of the sources of all kinds of diseases. This study aimed to clarify the symptoms and findings associated with hie and contribute to increased precision in hie diagnosis. During 2005-2006, data from interviews of 1691 patients during their initial visit to the Kampo Clinic of Keio University Hospital were analyzed using a classification and regression tree (CART) analysis, a data mining technique. Symptoms and findings characteristic of each group are follows as, postmenopausal women: fatigability, absence of lower abdominal pain, and absence of hot flashes of feet: women with menstruation: leg swelling, knee pain, and abdominal pain; men: insomnia, leg weakness, and absence of excess saliva. From the perspective of Kampo medicine the result suggested that the feature of hie condition in postmenopausal women, women with menstruation, and men is statistically different.

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Section: Introductionmentioning

confidence: 99%

Clinical Data Mining Related to the Japanese Kampo Concept “Hie” (Oversensitivity to Coldness) in Men and Pre‐ and Postmenopausal Women

Tokunaga

Munakata

Katayama

et al. 2014

Evidence-Based Complementary and Alternative Medicine

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“…According to one Japanese survey, approximately 60% of the Japanese population suffer from cold syndrome, especially extremity coldness [18]. Facing health care issues, the Japanese government approved insurance coverage of Kampo treatment for CHH [19]. However, even though there have been increasing numbers of people experiencing CHH in Korea, policymakers have not yet allowed for broader TKM health insurance coverage or better development of a TKM welfare program.…”

Section: Discussionmentioning

confidence: 99%

The efficacy and safety of Danggui-Sayuk-Ga-Osuyu-Saenggang-tang on Korean patients with cold hypersensitivity in the hands: study protocol for a pilot, double-blind, randomized, placebo-controlled, parallel-group clinical trial

Cho

et al. 2017

Trials

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BackgroundIn recent years, cold hypersensitivity in the hands (CHH) has become a common ailment of women in Korea. It can lead to gynecological problems such as irregular menstruation, miscarriage, and infertility. Traditionally, Korean herbal medicine has been the primary treatment method used to balance thermoregulation in the human body; however, its effectiveness has not been confirmed through systematic study. Thus, in this trial, we will investigate the feasibility of a full randomized clinical trial, Danggui-Sayuk-Ga-Osuyu-Saenggang-tang (DSGOST) in Korean women with CHH.MethodsThis study will be a pilot, multicenter, double-blind, randomized, parallel-group, two-arm, placebo-controlled clinical trial. A total of 66 participants will be randomly divided into two groups, a DSGOST treatment group and a placebo control group, in a 1:1 ratio using a web-based randomization system. Each group will take DSGOST or placebo three times daily for 6 weeks. The primary outcome will be measured using Visual Analogue Scale (VAS) scores of CHH. Secondary outcomes will include changes in skin temperature of the hands, Clinical Global Impressions (CGI) scale scores, recovery rate of skin temperature of the hands after the cold stress test, and the Korean version of the WHO Quality of Life Scale, abbreviated version (WHOQOL-BREF).DiscussionThis trial will be the first trial to reflect the newly defined disease range of CHH which was compiled by Korean medicine expert consensus. This study will provide considerable evidence for further large-scale trials and general clinical guidelines for CHH in the Korean medical field.Trial registrationThis study is registered at ClinicalTrials.gov, ID: NCT02645916. Registered on 30 December 2015.Electronic supplementary materialThe online version of this article (doi:10.1186/s13063-017-2002-8) contains supplementary material, which is available to authorized users.

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“…The non-specialist variable set included age, sex, BMI, subjective symptoms, and the two essential and predictable traditional medicine pattern diagnoses—excess–deficiency and heat–cold—according to Kampo specialists. The specialist variable set included ten abdominal examination findings, which are especially important traditional measurement methods, and eight body constituent patterns, in addition to all of the predictor variables of the non-specialist variable set [8, 17]. …”

Section: Methodsmentioning

confidence: 99%

Predicting Japanese Kampo formulas by analyzing database of medical records: a preliminary observational study

Yoshino

Katayama

Horiba

et al. 2016

BMC Med Inform Decis Mak

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BackgroundApproximately 90 % of physicians in Japan use Kampo medicine in daily practice. However, it is a challenge for physicians who do not specialize in Kampo medicine to select a proper Kampo formula out of the 148 officially approved formulas, as the decision relies on traditional measurements and traditional medicine pattern diagnoses. The present study tries to evaluate the feasibility of a decision support system for frequently used Kampo formulas.MethodsOur study included 393 patients who visited the Kampo Clinic at Keio University Hospital for the first time between May 2008 and March 2013. We collected medical records through a browser-based questionnaire system and applied random forests to predict commonly prescribed Kampo formulas.ResultsThe discriminant rate was the highest (87.0 %) when we tried to predict a Kampo formula from two candidates using age, sex, body mass index, subjective symptoms, and the two essential and predictable traditional medicine pattern diagnoses (excess–deficiency and heat–cold) as predictor variables. The discriminant rate decreased as the candidate Kampo formulas increased, with the greatest drop occurring between three (76.7 %) and four (47.5 %) candidates. Age, body mass index, and traditional medicine pattern diagnoses had higher importance according to the characteristics of each Kampo formula when we utilized the prediction model, which predicted a Kampo formula from among three candidates.ConclusionsThese results suggest that our decision support system for non-specialist physicians works well in selecting appropriate Kampo formulas from among two or three candidates. Additional studies are required to integrate the present statistical analysis in clinical practice.

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Kampo in Women's Health: Japan's Traditional Approach to Premenstrual Symptoms

Cited by 12 publications

References 29 publications

Clinical Data Mining Related to the Japanese Kampo Concept “Hie” (Oversensitivity to Coldness) in Men and Pre‐ and Postmenopausal Women

Clinical Data Mining Related to the Japanese Kampo Concept “Hie” (Oversensitivity to Coldness) in Men and Pre‐ and Postmenopausal Women

The efficacy and safety of Danggui-Sayuk-Ga-Osuyu-Saenggang-tang on Korean patients with cold hypersensitivity in the hands: study protocol for a pilot, double-blind, randomized, placebo-controlled, parallel-group clinical trial

Predicting Japanese Kampo formulas by analyzing database of medical records: a preliminary observational study

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