Momordica charantia stem extract mediated biogenic synthesis of silver nanoparticles: optical and antimicrobial efficacy

Akinsiku, Anuoluwa Abimbola; Ajanaku, K. O.; Adebisi, Abimbola A.; Edobor-Osoh, A.; Aladesuyi, Olanrewaju A.; Samson, Taiwo Olugbenga; Dare, Enock O.

doi:10.1088/1757-899x/509/1/012018

Cited by 7 publications

(4 citation statements)

References 26 publications

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“…The proposed biosynthesis reaction took place through the active sites created by nitrogen present in the alkaloids of N. tabacum, resulting in the attachment of methylene groups to nitrogen on the surface of the Ag nanoparticles as proposed in our earlier study [33]. There appears to be no peak in the carbonyl (C=O) region characteristic of carbohydrates and glycosides (Scheme 1).…”

Section: ■ Results and Discussionmentioning

confidence: 70%

Nicotiana tabacum Mediated Green Synthesis of Silver Nanoparticles and Ag-Ni Nanohybrid: Optical and Antimicrobial Efficiency

2020

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A sustainable method was considered for the preparation of nanosilver and its allied nanoparticles. Nicotiana tabacum, an abused plant, has found an application as a bio-chemical instead of lethal chemical in the synthesis of nanoparticles. As part of green chemistry implementation, double distilled water was the solvent used for extraction. The phytochemicals present were analyzed using standard procedures. Nanoparticle synthesis was carried out at varying precursor concentrations, and the reaction was monitored with a UV-visible spectrophotometer. Another optical characterization was also achieved with photoluminescence. Other characterization involved: X-ray diffraction (XRD), transmission electron microscopy (TEM), energy dispersive X-ray (EDS), and Fourier transform infrared spectroscopy techniques (FTIR). A matched phase identification of nanosilver resembled a face-centered cubic of Ag with a mean size of 11.68 nm, and a lattice constant of 4.0862 Å. The Ag NPs displayed activity against clinical isolates of fungi, Gram-positive, and Gram-negative bacteria as the growth inhibition was significant at P < 0.05. Ag NPs obtained from the Nicotiana tabacum proved to be an antibacterial and antifungal candidate, unlike the Ag NPs derived using chemical and physical methods, which were harmful for this purpose. Both the Ag NPs and Ag-Ni NPs displayed optical activity, which qualifies them for application in visual materials.

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Section: ■ Results and Discussionmentioning

confidence: 70%

Nicotiana tabacum Mediated Green Synthesis of Silver Nanoparticles and Ag-Ni Nanohybrid: Optical and Antimicrobial Efficiency

2020

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“…In a study conducted by Akinsiku et al using synthetic nanoparticles from Momordica charantia stems on some bacteria, the synthesized nanoparticles showed antibacterial and inhibitory effects. The results also showed that the lowest inhibitory concentration and the least destructive concentration were 12.5 mg/mL and the lowest activity of these particles was detected against P. aeruginosa with MIC of 50 mg/mL and MBC of 100 mg/mL (28).…”

Section: Discussionmentioning

confidence: 92%

Investigating Antibacterial Properties of Tecomella undulata and Momordica charantia Plant Extracts on Some Pathogenic Bacteria

2019

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Background: Today, due to microbial resistance to antibiotics, herbs and their compounds are commonly used as alternative antibiotics. The extracts of some plants can inhibit the growth of microorganisms as new antimicrobial agents. Thus, they can have great applications in medical science and food industry. Objectives: The aim of this study was to investigate the antibacterial effects of Tecomella undulata and Momordica charantia extracts on Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Shigella dysenteriae. Methods: After the identification and collection of plant samples, they were dried and underwent extraction using a rotary machine following the soaking method. The microdilution method was used to determine the antibacterial properties of the extracts on standard strains of Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Shigella dysenteriae. Results: The minimum inhibitory concentrations of Tecomella undulata extract against the studied bacteria were 1.87 to 3.75 mg/ml. The highest lethal concentration of leaf extract was 15 mg/mL and the lowest lethal concentration of Momordica charantia extract was 1.87 to 3.75 mg/mL. The highest Momordica charantia extract concentration was 15 mg/mL and Shigella dysenteriae were eliminated at this concentration, Conclusions: The results of this study revealed that various concentrations of the hydroalcoholic extract of Tecomella undulata and Momordica charantia had inhibitory effects on human pathogens.

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“…Among these extracts, chloroform extracts were most effective against S.paratyphi because, larger zone of inhibition were observed in chloroform extracts as compared to other solvents 33 . Against S. aureus, highest zone of inhibition was seen with methanol extract of hybrid seed 34 . Chloroform extract of wild fruit showed, the highest zone of inhibition P-13 against E.coli 35 .…”

Section: Discussionmentioning

confidence: 97%

Phytochemical Analysis and Antimicrobial Activity of Mimordica Charantia Medicinal Plant Against Selected Common Human Pathogenic Microorganisms

Padwad¹,

Lambat²,

Lambat³

et al. 2022

Int J Pharma Bio Sci

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Momordica charantia is a plant belonging to Cucurbitaceae family known for decades for its medicinal and nutritional value. The objective of the present study was to do qualitative evaluation and compare the antibacterial activity of M. charantia leaf, seeds and fruits. Results of our study showed that hybrid seed methanol extract had more active phytoconstituents like alkaloid, carbohydrate, saponin, proteins, resin, flavonoid, diterpens, reducing sugars than other extracts of fruit, leaf and seed of wild and hybrid varieties of M. charantia extracted using different solvents. Carbohydrate, phytosterol, and proteins are mostly present in all extracts of Mimordica charantia. Flavonoids are significantly present in seeds. So hybrid seed methanol extract can be considered as the main source of above mentioned phytochemicals to facilitate pharmaceutical industries. Methanol extracts of hybrid seed exhibited highest zone of inhibition against Salmonella paratyphi A (30±0.64mm) & Staphylococcus aureus (26±0mm) and chloroform extract of wild fruit showed highest activity against E.coli (22.5±0.64mm).Hence these extracts may be used to treat infectious diseases, surgical wounds, skin lesions, salmonellosis, enteric fever, food poisoning. The purpose of the current study was to investigate antimicrobial activity of M. charantia, apart from being used as anti-psoriatic drugs and this plant earlier have been used also as antibacterial agents, hence the activity was also carried out against other organisms such as Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Salmonella typhi and Aspergillus niger. Further phytochemical analysis (using techniques like TLC and HPLC) will be necessary to isolate the active constituents and clinical studies are required to understand the mechanism and the actual efficacy of these extracts in treating various infections and skin diseases. This will have significant importance in pharmaceutical and herbal industries.

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Momordica charantia stem extract mediated biogenic synthesis of silver nanoparticles: optical and antimicrobial efficacy

Cited by 7 publications

References 26 publications

<i>Nicotiana tabacum</i> Mediated Green Synthesis of Silver Nanoparticles and Ag-Ni Nanohybrid: Optical and Antimicrobial Efficiency

<i>Nicotiana tabacum</i> Mediated Green Synthesis of Silver Nanoparticles and Ag-Ni Nanohybrid: Optical and Antimicrobial Efficiency

Investigating Antibacterial Properties of Tecomella undulata and Momordica charantia Plant Extracts on Some Pathogenic Bacteria

Phytochemical Analysis and Antimicrobial Activity of Mimordica Charantia Medicinal Plant Against Selected Common Human Pathogenic Microorganisms

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