Mycobacterium peregrinum Skin Infection

Abstract

Background: Mycobacterium peregrinum is a rapidly growing mycobacterium (RGM) that rarely causes skin infections. The correct identification of the specific RGM infecting the skin will enhance therapeutic success. Objective: To highlight the importance of rapid and precise identification of the Mycobacterium involved in skin infections in order to enhance therapeutic success. Methods: We describe an RGM skin infection in an immunocompetent patient. Results: Classic methods (biochemical tests and culture) of RGM identification are time-consuming, and the histopathological features are not specific. Some molecular methods are reliable but expensive. The PRAhsp-65 is a simple procedure that is helpful in identifying the specific agent of an RGM. Conclusion: Although skin infections caused by M peregrinum are rare, they represent a substantial clinical challenge. Specific and more effective treatment options depend on the development of precise and rapid methods for identifying mycobacterial species.

Mycobacterium peregrinum Pacemaker Pocket Infection: A Case Report and Review of the Literature

“…There have been several published cases related to M. peregrinum causing infections such as surgical site, cardiac devices, soft tissue, and central catheters [ 3 – 7 , 13 – 15 ]. To our knowledge, there have only been three reported cases of M. peregrinum infection associated with cardiac devices, including our patient.…”

“…Mycobacterium peregrinum is one of the RGM that belong to the Mycobacterium fortuitum complex and has been rarely reported to infect humans [ 3 ]. Overall, the incidence and importance of infections by RGM have been on the rise, and M. peregrinum has been associated with central lines, surgical sites, soft tissue, and skin infections [ 5 – 7 ]. Here, we present a case of a permanent pacemaker pocket site infection caused by M. peregrinum.…”

Disseminated Mycobacterium peregrinum and Mycobacterium avium infection in a patient with AIDS: A case report and review of literature

“…M. peregrinum is a RGM and belongs to the M. fortuitum complex. Skin and soft tissue infection, pneumonia, bacteremia (catheter-related and primary infection), implantable cardioverter device infection, and tonsillar abscess by M. peregrinum have been reported, in which skin and soft tissue infection is the most common form of infection [3] , [4] , [5] , [6] , [7] , [8] , [9] , [10] , [11] . Disseminated infection by M. peregrinum is rare as M. fortuitum complex rarely causes disseminated infections compared to other pathogenic RGM, especially M. chelonae and M. abscessus [1] .…”