Mycoplasma hyorhinis Swine Arthritis III. Modified Disease in Piney Woods Swine

Abstract

Piney Woods miniature swine, when injected with Mycoplasma hyorhinis, develop an acute arthritis. The disease in these animals is limited clinically, microbiologically, and pathologically to a mild acute illness without the more chronic and destructive features noted in a previous study of the experimental disease in Yorkshire swine.

Virulence and Inoculation Route Influence the Consequences of Mycoplasma hyorhinis Infection in Bama Miniature Pigs

“…The pigs were euthanized at 21 dpi. (A-D) The development of pericarditis (A), pleuritis (B), peritonitis (C) and arthritis (D) were scored to reflect the relative severity according to previously defined criteria ( 14 ). (E) Total score was calculated as the sum of the scores of all four tissues.…”

“…The acute clinical signs usually subside after 10 to 14 days. In case of arthritis, lameness and swollen joints may persist for 2 to 3 months ( 13 , 14 ). In this study, the clinical signs of challenged animals began to resolve after 10 days postinoculation.…”

Mycoplasma infections as models of chronic joint inflammation

“…A genetic component in the development of arthritis is also apparent in the wide range of susceptibilities of different mouse strains to M arthritidis and M pulmonis (19)(20)(21). A similar genetic component may play a role in susceptibility of swine to M hyorhinis (22).…”