n-Butyl Nitrite

Copper(i)-catalyzed sulfonylative Suzuki–Miyaura cross-coupling

“…A variety of methods are available for the synthesis of sulfones, 6,7 including a number of transition metal-catalyzed approaches. 8 However, many of these classical syntheses are either multi-step, or employ harmful, non-selective reagents, significantly detracting from their utility.…”

“…1b), are common motifs in designed materials, and they serve as versatile intermediates for organic synthesis – this absence is striking. 6 In this Edge Article, we show that by using a copper( i ) catalyst, a high yielding sulfonylative-Suzuki–Miyaura cross-coupling reaction is possible.…”

Ag(I)-Promoted Dehydroxylation and Site-Selective 1,7-Disulfonylation of Diaryl(1H-indol-2-yl)methanols

“…Molecules containing an arylsulfone motif often exhibit obvious bioactivity, for instance, anticancer, anti-HIV, antibacterial, and are used widely in therapeutica areas such as leprosy, depression, and cardiac diseases . Sulfones also play important roles in synthetic chemistry and materials science . It was also found that the introduction of an arylsulfone fragment into heterocycles would increase their pharmacological activity .…”

Highly Selective and Switchable Access to Tetrasubstituted Alkenyl Sulfones and Naphthyl Sulfones: 1,4-Aryl Migration versus Cyclization

“…The sulfonyl group is a ubiquitous structural motif found in many bioactive molecules, agrochemicals, and marketed drugs . It also serves as a versatile building block in organic synthesis .…”