N-Chloro-3-methyl-2,6-diphenylpiperidin- 4-one (NCP) – An Efficient, Mild, Stable Oxidant for Cleavage of Carbon-Nitrogen Double Bonds of Oximes

Abstract

Aldoximes and ketoximes are effectively deoximated to regenerate the carbonyl compound by an efficient, mild, stable oxidant N-chloro-3-methyl-2,6-diphenylpiperidin-4-one (NCP).

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“…Antibacterial Activity 13,15,19,22 : These synthesis of a series of these derivatives was carried out and the obtained compounds IVa-e were tested for their in vitro antibacterial activity against some Table 1. The antibacterial screening put in evidance that all the synthesized novel 3-(5-substituted phenyl-1, 3, 4-oxdiazol-2-yl) pyridines IV b and IV e exhibited a wide spectrum of antibacterial profile in vitro against the test organisms.…”

Synthesis, Characterization of Substituted Piperdin-4-ones with Dichloro(cyclooctadiene)palladium(II)

“…2,6-Diphenyl-4-piperidone and their metal complexes have a variety of applications in numerous scientific areas. By exhibiting a wide range of pharmacological activities [6][7][8][9][10][11][12] a series of 2,6-diphenyl-4-piperidone were synthesized by different dialkyl ketone, aromatic aldehyde and ammonium acetate by Mannich condensation reaction 13 . The formation of an interesting array of new compounds we reported the synthesis of substituted 2, 6-diphenyl-4-piperidone with palladium metal by the formation of an interesting array of new compounds.…”