N′-[(E)-5-Bromo-2-hydroxy-3-methoxybenzylidene]-4-methoxybenzohydrazide monohydrate

Abstract

In the title compound, C16H15BrN2O4·H2O, the hydrazide mol­ecule is nearly planar, with a largest deviation from the mean plane through the non-H atoms of 0.106 (4) Å and a dihedral angle between the benzene rings of 1.98 (16)°. This mol­ecule adopts an E conformation about the C=N bond and an intra­molecular O—H⋯N hydrogen bond increases the rigidity. In the crystal, some mol­ecules of the title hydrazide are replaced by mol­ecules of its 6-bromo isomer, and the Br atom from this admixture mol­ecule was refined to give a partial occupancy of 0.0523 (13). The hydrazide and water mol­ecules are linked through classical N—H⋯O and O—H⋯O hydrogen bonds, forming layers parallel to (110). C—H⋯π inter­actions are also present.

4-{(E)-[2-(Pyridin-3-ylcarbonyl)hydrazinylidene]methyl}phenyl acetate

“…1) crystallizes in the monoclinic space group P2 1 /n. This molecule adopts an E configuration with respect to the C7=N3 bond and it exists in the amido form with a C6=O1 bond length of 1.2277 (18) Å which is very close to the reported C=O bond length of a related structure (Reshma et al, 2012). The O1 and N2 atoms are in a Z configuration with respect to C6-N2 having a torsion angle of 9.9 (3)°.…”

“…For the synthesis of related compounds, see: Emmanuel et al (2011). For related structures, see: Reshma et al (2012).…”

N′-[(E)-5-Bromo-2-hydroxy-3-methoxybenzylidene]benzohydrazide monohydrate

“…1) crystallizes in the monoclinic space group P2 1 2 1 2 1 . This molecule adopts an E configuration with respect to the C7=N1 bond and it exists in the amido form with a C8=O3 bond length of 1.222 (5) Å which is very close to the reported C=O bond length of a related structure (Reshma et al, 2012). The O3 and N1 atoms are in a Z configuration with respect to C8-N2 having a torsion angle of -0.3 (7)°.…”