“…Many studies have now documented that obese children and adults have lower serum concentrations of antioxidants, including vitamin E, vitamin C, carotenoids, and selenium. [100][101][102] This may be a result of decreased intakes of these nutrients 103,104 but may also relate to increased systemic and adipose tissue-specific oxidative stress among obese persons leading to increased oxidative catabolism of these nutrients. 105,106 Obesity has also been found to be a risk factor for low levels of circulating vitamin D. 101,[107][108][109][110] The reasons for low circulating vitamin D levels in obesity include adipose tissue sequestration and decreased bioavailability of vitamin D. 110,111 With regard to fatty acids, the changes in polyunsaturated fatty acid composition of diets in Western society, with the decrease in n-3 and increase in n-6 fatty acids that has been postulated to affect asthma incidence, may also have a role in the increased prevalence of obesity.…”