<i>p</i>-Hexafluoroisopropanol phenyl functionalized graphene for QCM based detection of dimethyl methylphosphonate, a simulant of the nerve agent sarin

Shaik, Mahabul; Rao, Venkat K.; Ramana, G. Venkata; Halder, Mintu; Gutch, P. K.; Pandey, P. N.; Jain, Rajeev

doi:10.1039/c7ra12272a

Cited by 26 publications

(15 citation statements)

References 38 publications

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“…The selectivity of carbon nanotubes (CNTs) was greatly enhanced after functionalizing with hexafluorobisphenol A (6FBPA) owing to forming strong hydrogen bonding with DMMP . Hexafluoroisopropanol (HFIP) functionalized graphene showed excellent selectivity toward DMMP in comparison with unfunctionalized graphene, as reported by Shaik et al . Hexafluoroisopropanol (HFIP, C 3 H 2 F 6 O) is an organic group that has active hydroxyl groups on its sides, which enhance the selectivity toward DMMP by forming hydrogen bonding between the oxygen on DMMP molecules and hydroxy groups in HFIP .…”

Section: Introductionmentioning

confidence: 88%

“…On exposure to CWA, these toxins directly attack the nervous system and create covalent bonds with the serine residue at the active site of the enzymes, which causes inhibition of the enzyme acetylcholinesterase. This inhibition will lead to rapid death owing to reduced breakdown of acetylcholine in the nervous system . Thus, the early detection of these nerve agents in urban areas has become a critical issue since the sarin attack on the Tokyo subway in 1995 .…”

Section: Introductionmentioning

confidence: 99%

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HFIP‐Functionalized Co₃O₄ Micro‐Nano‐Octahedra/rGO as a Double‐Layer Sensing Material for Chemical Warfare Agents

Alali

Liu

Chen

et al. 2019

Chemistry A European J

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Semiconductor metal oxides (SMO)‐based gas‐sensing materials suffer from insufficient detection of a specific target gas. Reliable selectivity, high sensitivity, and rapid response–recovery times under various working conditions are the main requirements for optimal gas sensors. Chemical warfare agents (CWA) such as sarin are fatal inhibitors of acetylcholinesterase in the nerve system. So, sensing materials with high sensitivity and selectivity toward CWA are urgently needed. Herein, micro‐nano octahedral Co3O4 functionalized with hexafluoroisopropanol (HFIP) were deposited on a layer of reduced graphene oxide (rGO) as a double‐layer sensing materials. The Co3O4 micro‐nano octahedra were synthesized by direct growth from electrospun fiber templates calcined in ambient air. The double‐layer rGO/Co3O4‐HFIP sensing materials presented high selectivity toward DMMP (sarin agent simulant, dimethyl methyl phosphonate) versus rGO/Co3O4 and Co3O4 sensors after the exposure to various gases owing to hydrogen bonding between the DMMP molecules and Co3O4‐HFIP. The rGO/Co3O4‐HFIP sensors showed high stability with a response signal around 11.8 toward 0.5 ppm DMMP at 125 °C, and more than 75 % of the initial response was maintained under a saturated humid environment (85 % relative humidity). These results prove that these double‐layer inorganic–organic composite sensing materials are excellent candidates to serve as optimal gas‐sensing materials.

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Section: Introductionmentioning

confidence: 88%

Section: Introductionmentioning

confidence: 99%

HFIP‐Functionalized Co₃O₄ Micro‐Nano‐Octahedra/rGO as a Double‐Layer Sensing Material for Chemical Warfare Agents

Alali

Liu

Chen

et al. 2019

Chemistry A European J

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“…The same benzyl alcohol has been used by Rao and co‐workers [84] . In particular, they functionalized a gold coated quartz crystal microbalance (QCM) sensor with graphene‐ p ‐hexafluoroisopropanol phenyl (HFIPP‐GR), thus obtaining a nanosensor able to detect DMMP by hydrogen bond.…”

Section: Sensing By Supramolecular Approachmentioning

confidence: 99%

“…The same benzyl alcohol has been used by Rao and coworkers. [84] In particular, they functionalized a gold coated quartz crystal microbalance (QCM) sensor with graphene-phexafluoroisopropanol phenyl (HFIPP-GR), thus obtaining a nanosensor able to detect DMMP by hydrogen bond. The reversible detection of DMMP was performed by QCM's oscillating frequency variation, with a limit of detection of 5 ppm.…”

Section: Sensing By Nanosensorsmentioning

confidence: 99%

Supramolecular Sensing of Chemical Warfare Agents

et al. 2021

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Chemical warfare agents are a class of organic molecules used as chemical weapons due to their high toxicity and lethal effects. For this reason, the fast detection of these compounds in the environment is crucial. Traditional detection methods are based on instrumental techniques, such as mass spectrometry or HPLC, however the use of molecular sensors able to change a detectable property (e. g., luminescence, color, electrical resistance) can be cheaper and faster. Today, molecular sensing of chemical warfare agents is mainly based on the “covalent approach”, in which the sensor reacts with the analyte, or on the “supramolecular approach”, which involves the formation of non‐covalent interactions between the sensor and the analyte. This Review is focused on the recent developments of supramolecular sensors of organophosphorus chemical warfare agents (from 2013). In particular, supramolecular sensors are classified by function of the sensing mechanism: i) Lewis Acids, ii) hydrogen bonds, iii) macrocyclic hosts, iv) multi‐topic sensors, v) nanosensors. It is shown how the supramolecular non‐covalent approach leads to a reversible sensing and higher selectivity towards the selected analyte respect to other interfering molecules.

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“…In this work, CNT-mat type sensors have been used as they have high sensitivity at ambient temperature and are cost effective. Furthermore, their selectivity is tunable by adding polymers in the CNT-mat [8]- [10] The choice of the features which are extracted from the raw responses of the sensors is crucial for E-nose systems. Transient features such as integrals and maximum derivatives have been showned to be reliable features [11].…”

Section: Dga For Fundings 2016337mentioning

confidence: 99%

An Electronic Nose Prototype for the On-Field Detection of Nerve Agents

Laquintinie¹,

Sachan

Feller

et al. 2018

2018 Ieee Sensors

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This paper presents a cost effective electronic nose prototype for the detection of 1.6 ppm of dimethyl methylphosphonate (DMMP) in a complex background. The device comprises of seven cross-sensitive carbon nanotube mat (CNT-mat) type sensors, an impedance measurement circuit and a microcomputer for data pre-treatment and classification stages. This study focused on the detection of DMMP in a gas mixture, using the responses of the sensors before they reach a stable and repeatable behavior. Even with this major constraint, the support vector machine used for classification reached 98% precision for the recognition of the samples.

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p-Hexafluoroisopropanol phenyl functionalized graphene for QCM based detection of dimethyl methylphosphonate, a simulant of the nerve agent sarin

Abstract: The hexafluoroisopropanol moiety was grafted onto graphene and used as a sensing layer for the detection of a nerve agent simulant using QCM.

Cited by 26 publications

References 38 publications

HFIP‐Functionalized Co₃O₄ Micro‐Nano‐Octahedra/rGO as a Double‐Layer Sensing Material for Chemical Warfare Agents

HFIP‐Functionalized Co₃O₄ Micro‐Nano‐Octahedra/rGO as a Double‐Layer Sensing Material for Chemical Warfare Agents

Supramolecular Sensing of Chemical Warfare Agents

An Electronic Nose Prototype for the On-Field Detection of Nerve Agents

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p-Hexafluoroisopropanol phenyl functionalized graphene for QCM based detection of dimethyl methylphosphonate, a simulant of the nerve agent sarin

Abstract: The hexafluoroisopropanol moiety was grafted onto graphene and used as a sensing layer for the detection of a nerve agent simulant using QCM.

Cited by 26 publications

References 38 publications

HFIP‐Functionalized Co3O4 Micro‐Nano‐Octahedra/rGO as a Double‐Layer Sensing Material for Chemical Warfare Agents

HFIP‐Functionalized Co3O4 Micro‐Nano‐Octahedra/rGO as a Double‐Layer Sensing Material for Chemical Warfare Agents

Supramolecular Sensing of Chemical Warfare Agents

An Electronic Nose Prototype for the On-Field Detection of Nerve Agents

Contact Info

Product

Resources

About

HFIP‐Functionalized Co₃O₄ Micro‐Nano‐Octahedra/rGO as a Double‐Layer Sensing Material for Chemical Warfare Agents

HFIP‐Functionalized Co₃O₄ Micro‐Nano‐Octahedra/rGO as a Double‐Layer Sensing Material for Chemical Warfare Agents