<i>SAYE:</i> The Story of an Antimalarial Phytomedicine from Burkina Faso

Dakuyo, Z.; Meda, Aline Lamien; Da, Ollo; Kiendrebéogo, Martin; Traoré-Coulibaly, Maminata; Novak, Johannes; Benoit‐Vical, Françoise; Weisbord, Emma; Willcox, Merlin

doi:10.1089/acm.2014.0147

Cited by 4 publications

(2 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Concerning the effectiveness of different plant found in informant, it could be supported by the previous antimalarial investigations (Table 1), particularly the three most preference plants namely C. planchonii, C. alata and P. crassipes biological proprieties evaluated by searcher Burkinabè [17,39,42]. Although traditional healer and herbalists were convinced of non-toxicity of these plants, it is found that in previous studies that plant extract could present some toxicity (Table 1).…”

Section: Discussionsupporting

confidence: 64%

Availability Evaluation of Twelve Antimalarial Medicinal Plants from Western Regions of Burkina Faso

Compaoré¹

2018

JDMP

View full text Add to dashboard Cite

Major research contributions in ethnopharmacology have generated vast amount of data associated with medicinal plants in Burkina Faso. Despite the relatively abundant literature on local medicinal plants supported by an institutional environment in favor of promoting traditional medicine, any national pharmacopoeia document or monographs on antimalarial medicinal plants aren't currently available. The aim of this study is to evaluate the knowledge and perception of traditional healers on the effectiveness and availability of 12 antimalarial plants from Burkina Faso. The survey was carried out on 12 antimalarial plants from western region during January-March 2013. The informants were 100 traditional healers and herbalist from the Western region, which gathered in association affiliated to General Directorate of Pharmacy, Medicines and Laboratories. A semi-structured and open questionnaire and herbarium were used for plant identification. The data showed that Securidaca longepedunculata (66%) and Zanthoxylum zanthoxyloides (64%) was the lowest available followed by Pavetta crassipes (57%), Argemone mexicana (48%) and Cochlospermum planchonii (44%). The root uses of C. planchonii (51%), S. longepedunculata (24%) and Z. zanthoxyloides (11%) were probably their threat. S. longepedunculata, Z. zanthoxyloides and P. crassipes are really in endangered due to their large medicinal uses particularly in malaria treatment. It need a new policy management and integrated breeding for these plants.

show abstract

Section: Discussionsupporting

confidence: 64%

Availability Evaluation of Twelve Antimalarial Medicinal Plants from Western Regions of Burkina Faso

Compaoré¹

2018

JDMP

View full text Add to dashboard Cite

show abstract

“…The Burkina Faso government also encourages and supports the development of traditional medicine, which is widely used by the populations and even medicine practitioners [70][71][72]. The country's weak pharmacovigilance capacities explains the low number of traditional drugs available in pharmacies given the large number of medicinal plants used in the management of malaria [70,[73][74][75]. Continued support for pharmacovigilance activities is required to have safe products that will diversify the medicines offered and reduce the selection pressure on modern anti-malarial combinations.…”

Section: Pressure Due To Limited Acts Used In the Countrymentioning

confidence: 99%

The impact of anti-malarial markets on artemisinin resistance: perspectives from Burkina Faso

Guissou,

Amaratunga,

de Haan

et al. 2023

Malar J

View full text Add to dashboard Cite

Background Widespread artemisinin resistance in Africa could be catastrophic when drawing parallels with the failure of chloroquine in the 1970s and 1980s. This article explores the role of anti-malarial market characteristics in the emergence and spread of arteminisin resistance in African countries, drawing on perspectives from Burkina Faso. Methods Data were collected through in-depth interviews and focus group discussions. A representative sample of national policy makers, regulators, public and private sector wholesalers, retailers, clinicians, nurses, and community members were purposively sampled. Additional information was also sought via review of policy publications and grey literature on anti-malarial policies and deployment practices in Burkina Faso. Results Thirty seven in-depth interviews and 6 focus group discussions were conducted. The study reveals that the current operational mode of anti-malarial drug markets in Burkina Faso promotes arteminisin resistance emergence and spread. The factors are mainly related to the artemisinin-based combination therapy (ACT) supply chain, to ACT quality, ACT prescription monitoring and to ACT access and misuse by patients. Conclusion Study findings highlight the urgent requirement to reform current characteristics of the anti-malarial drug market in order to delay the emergence and spread of artemisinin resistance in Burkina Faso. Four recommendations for public policy emerged during data analysis: (1) Address the suboptimal prescription of anti-malarial drugs, (2) Apply laws that prohibit the sale of anti-malarials without prescription, (3) Restrict the availability of street drugs, (4) Sensitize the population on the value of compliance regarding correct acquisition and intake of anti-malarials. Funding systems for anti-malarial drugs in terms of availability and accessibility must also be stabilized.

show abstract

Quality assessment and antiplasmodial activity of West African Cochlospermum species

et al. 2015

View full text Add to dashboard Cite

SAYE: The Story of an Antimalarial Phytomedicine from Burkina Faso

Cited by 4 publications

References 46 publications

Availability Evaluation of Twelve Antimalarial Medicinal Plants from Western Regions of Burkina Faso

Availability Evaluation of Twelve Antimalarial Medicinal Plants from Western Regions of Burkina Faso

The impact of anti-malarial markets on artemisinin resistance: perspectives from Burkina Faso

Quality assessment and antiplasmodial activity of West African Cochlospermum species

Contact Info

Product

Resources

About