Datura stramonium intoxication in two children

Abstract

Datura stramonium is a toxic plant member of the Solanaceae family. Its consumption may result in severe anticholinergic toxicity. We report the intoxication of 5-and 4-year-old brothers with Datura stramonium, which presented in two different manners. The first child presented agitation, hallucination and mydriasis that improved rapidly with benzodiazepine medication. The second presented comatose, mydriasis and Babinski signs. Gastric lavage and activated charcoal administration were performed. The child was intubated and mechanically ventilated until consciousness improvement. Datura stramonium poisoning may be considered by physicians in case of acute onset of decreased consciousness or behaviour trouble associated with anticholinergic signs and symptoms.

Datura stramonium poisoning: a case report and review of the literature

“…This dose can be repeated as needed. But there are some contraindications, such as; cardiovascular disease, bronchospasm, intestinal obstruction, heart block, peripheral vascular disease, and bladder obstruction [9,10]. In our patient, gastric lavage and activated charcoal were performed after admission.…”

Pupillary Abnormalities in Childhood – 2 Case Presentations

“…Mierna intoxikácia sa prejaví jednostrannou alebo obojstrannou mydriázou [13], po požití odvaru alebo výluhu z rastliny dochádza k rýchlemu vzniku celkových prejavov. Pacient býva dezorientovaný, trpí halucináciami alebo upadá do letargie [18].Typický je aj celkový nepokoj, podráždenosť až agresivita. Taktiež dochádza k zvýšeniu telesnej teploty, suchosti slizníc, tachykardii a zvýšeniu systémového tlaku krvi [1].…”

“…Taktiež dochádza k zvýšeniu telesnej teploty, suchosti slizníc, tachykardii a zvýšeniu systémového tlaku krvi [1]. Zrenice sú mydriatické, s oslabenou až neprítomnou reakciou na osvit [18].…”

Datura Stramonium Zehirlenmesi Sonucu Antikolinerjik Sendrom: İki Olgu Sunumu

“…Gastrik lavaj ve aktif kömür uygulaması önemlidir ve antikolinerjik ajanlar midede uzun süre kalabileceğinden alımından sonraki 12 ile 24 saatte önerilir. Birçok çalışmada, datura stramonium zehirlenmesi olan hastaların çoğunluğu sadece genel destek tedavisine ve semptomatik tedaviye ihtiyaç duymuştur (12,13). Hastalarımız verilen ilk konservatif tedaviye iyi yanıt verdiklerinden, hiçbirinde fizostigmin veya takrin hidroklorür tedavisine ihtiyaç duyulmamıştır.…”