<i>The Revolution in Philosophy</i>. A. J. Ayer, W. C. Kneale, G. A. Paul, D. F. Pears, P. F. Strawson, G. J. Warnock, R. A. Wollheim With an introduction by Gilbert Ryle. London: MacMillan &amp; Co. Ltd., 1956. Pp. v, 126. $2.50.

Hinshaw, Virgil

doi:10.1086/287565

Cited by 11 publications

(17 citation statements)

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“…In addition, there were 2 cases where abscess formation occurred, and 1 diagnosed at autopsy, making a total of 62. This gives an incidence of 1: 1500, which is higher than the more commonly stated figure of 1: 2000, given for example by Merscheimer and Wattiker (1960) or Hinshaw (1963). Presumably this is because of the greater number of referred patients in our series.…”

contrasting

confidence: 50%

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Surgical Conditions Complicating Pregnancy Part 1. Acute Appendicitis — Real and Simulated

O’Neill

1969

Aust NZ J Obst Gynaeco

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contrasting

confidence: 50%

“…This was the only fetal loss in the group. Hinshaw (1963) states that the fetal loss increases from 3% to 30% once perforation has occurred. In Macbeth's (1960) series of surgical complications, there were 30 patients with acute appendicitis during pregnancy, and of the 8 in whom perforation had occurred, 5 were in the last trimester.…”

Section: Alive Deathmentioning

confidence: 99%

Surgical Conditions Complicating Pregnancy Part 1. Acute Appendicitis — Real and Simulated

O’Neill

1969

Aust NZ J Obst Gynaeco

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“…To determine the accuracy of our error estimation we have run 200 WMAP V-band Monte Carlo (MC) realizations. We simulated the signal by making random realizations of the CMB angular power spectrum as measured by WMAP, convolved with its measured symmetrized beam profile, to which we added random realizations of the white noise estimated for the V band (Hinshaw et al 2003). Sampling variance in the WMAP-APM cross-correlation was 1 Some of the results in this paper have been derived using HEALPIX (Górski et al 1998), http://www.eso.org/science/healpix thus evaluated by computing the correlation between the simulated V-band CMB maps (with WMAP Kp0 mask pixels removed) and the APM Survey.…”

Section: Data a N D S I M U L At I O N Smentioning

confidence: 99%

Measurement of the gravitational potential evolution from the cross-correlation betweenWMAPand the APM Galaxy Survey

Fosalba

Gaztañaga

2004

Monthly Notices of the Royal Astronomical Society

134

130

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Models with late‐time cosmic acceleration, such as the Λ‐dominated cold dark matter model, predict a freeze‐out for the growth of linear gravitational potential at moderate redshift z < 1, which can be observed as temperature anisotropies in the cosmic microwave background (CMB): the so‐called integrated Sachs–Wolfe (ISW) effect. We present a direct measurement of the ISW effect based on the angular cross‐correlation function, wTG(θ), of CMB temperature anisotropies and dark matter fluctuations traced by galaxies. We cross‐correlate the first‐year WMAP data in combination with the APM Galaxy Survey. On the largest scales, θ= 4°–10°, we detect a non‐vanishing cross‐correlation at 98.8 per cent significance level, with a 1σ error of wTG= 0.35 ± 0.14 μK, which favours large values of ΩΛ≃ 0.8 for flat Friedmann–Robertson–Walker models. On smaller scales, θ < 1°, the correlations disappear. This is contrary to what would be expected from the ISW effect, but the absence of correlations may be simply explained if the ISW signal was being cancelled by anti‐correlations arising from the thermal Sunyaev–Zeldovich effect.

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“…The complex between this NClO scFv and tern N9 sialidase has been crystallized for three-dimensional structural studies [14]. The structures of the complexes between N9 sialidase, isolated from tern [22] and whale [23], and the Fab fragments of monoclonal antibodies NC41 [24, 251 and NClO [26], which recognize overlapping epitopes on sialidase, have been determined. Sialidase is a homotetramer with circular fourfold symmetry and both of these complexes show four Fab molecules bound to the tetrameric antigen [24, 261. The protein sequences of the tern and whale N9 sialidases differ at 14 residues [27] but these substitutions have no effect on the Fabfsialidase interface [25] although they may influence the apparent binding constant for the interaction with NC41 Fab [28].…”

mentioning

confidence: 99%

Recombinant anti‐sialidase single‐chain variable fragment antibody

Kortt

Malby²,

Caldwell

et al. 1994

European Journal of Biochemistry

120

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The single-chain antibody variable fragment (scFv), with a 15-residue polypeptide linker (Gly,Ser),, of monoclonal antibody NClO was expressed in Escherichia coli and purified to homogeneity. This scFv molecule, refolded from 6 M guanidine hydrochloride, was predominantly a monomer of 27 kDa and was stable on storage at 4" and 20°C. At higher protein concentrations (= 5 mg/ml) dimer and higher-molecular-mass multimers were formed and freezing enhanced this aggregation. The dimer was not stable and dissociated to monomer at 20°C with a half-life of approximately 8 days. The higher-molecular-mass multimers and dimer dissociated to monomer in 60% ethylene glycol. Both the monomer and dimer were active and with tern N9 sialidase yielded complexes of 276 kDa and 569 kDa, respectively, indicating that four scFv molecules boundkialidase tetramer and that the dimer was bivalent and cross-linked two sialidase tetramers. Binding studies at low concentrations and using radiolabelled scFv indicated that the binding affinity of the dimer was approximately twofold higher than that of the monomer, and the binding affinities of the scFv were similar to that of the parent NClO antigen-binding fragment (Fab) molecule. A complex between tern N9 sialidase and NClO scFv was crystallized and the structure of the complex was solved at 0.3-nm resolution by X-ray diffraction. Comparison of this scFv/sialidase structure with the parent Fabhalidase structure revealed that the modes of attachment of scFv and Fab to sialidase were very similar. There was no discernible electron density for the peptide linker joining the variable heavy (V,) and variable light (V,) chains. A close interaction between two symmetryrelated scFv suggests that they may have crystallized as dimers.Monoclonal antibodies with their unique specificity and affinity are used widely as immunodiagnostic and therapeutic reagents [I] A scFv fragment of antibody NC10, which recognizes an epitope on influenza virus sialidase, was recently cloned and expressed in Escherichia coli [14]. The V, and V, domains were linked with the 15-residue peptide described above and also contained a hydrophilic octapeptide (FLAG) [19] at the C-terminus of the V, domain as an affinity label to aid in detection of the scFv. The purified, monomeric scFv was found to form dimers and higher-molecular-mass aggregates at a protein concentration greater than 5 mg/ml. Recently, the presence of dimers and higher-molecular-mass multimers

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The Revolution in Philosophy. A. J. Ayer, W. C. Kneale, G. A. Paul, D. F. Pears, P. F. Strawson, G. J. Warnock, R. A. Wollheim With an introduction by Gilbert Ryle. London: MacMillan & Co. Ltd., 1956. Pp. v, 126. $2.50.

Cited by 11 publications

References 0 publications

Surgical Conditions Complicating Pregnancy Part 1. Acute Appendicitis — Real and Simulated

Surgical Conditions Complicating Pregnancy Part 1. Acute Appendicitis — Real and Simulated

Measurement of the gravitational potential evolution from the cross-correlation betweenWMAPand the APM Galaxy Survey

Recombinant anti‐sialidase single‐chain variable fragment antibody

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