<i>β</i>‐Glucan supplementation, allergy symptoms, and quality of life in self‐described ragweed allergy sufferers

Talbott, Shawn M; Talbott, Julie A; Talbott, Tracy L; Dingler, Elaine

doi:10.1002/fsn3.11

Cited by 25 publications

(26 citation statements)

References 94 publications

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“…These results are consistent with studies linking protection against AM with LCPUFAs [ 12 , 34 ], prebiotics [ 21 , 22 , 35 ] and β-glucan [ 28 , 36 , 37 ]. Dietary LCPUFAs were associated with less atopic dermatitis and wheezing [ 12 , 34 ], and amelioration of symptoms in asthmatic children [ 38 ].…”

Section: Discussionsupporting

confidence: 91%

“…Likewise, prebiotic oligosaccharides support the immune system through stimulation of beneficial gut bacteria [ 17 – 20 ] and were associated with decreased respiratory infections and allergic diseases [ 21 – 24 ]. β-glucan, a polysaccharide derived from yeasts, fungi or bacteria, has also demonstrated immune-supporting properties [ 25 , 26 ], with data showing protection against respiratory infections and allergy in adults and children [ 26 – 28 ]. In a recent randomized clinical trial in 3- to 4-year-old children attending daycare in China, we demonstrated that daily consumption of a cow’s-milk based beverage (CMBB) containing a combination of nutrients including docosahexaenoic acid (DHA), the prebiotics polydextrose (PDX) and galactooligosaccharides (GOS), and yeast β-glucan, and enriched with micronutrients such as vitamin A, zinc and iron, was associated with fewer acute respiratory infections (ARI) compared to cow’s milk [ 29 ].…”

Section: Introductionmentioning

confidence: 99%

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Cow’s milk-based beverage consumption in 1- to 4-year-olds and allergic manifestations: an RCT

Pontes

Ribeiro

et al. 2015

Nutr J

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BackgroundNutrients such as docosahexaenoic acid (DHA), prebiotics and β-glucan have been associated with reduced incidence of respiratory illnesses and allergic manifestations (AM). Our objective was to assess if consumption of a cow’s milk-based beverage with these and other nutrients supports respiratory, gastrointestinal, and skin health in otherwise well-nourished, healthy children.MethodsIn this double-blind, randomized, controlled trial, healthy children (1–4 years of age) from two daycare centers in Brazil were fed three servings/day of a cow’s milk-based beverage (CMBB; n = 125) containing DHA, the prebiotics polydextrose (PDX) and galactooligosaccharides (GOS), β-glucan, and other key nutrients, or a control cow’s milk-based beverage (control; n = 131) for up to 28 weeks. Occurrence of respiratory infections, diarrheal disease and AM was assessed by study pediatricians and the number of episodes were analyzed with the Cochran-Mantel-Haenszel test and the Andersen-Gill model.ResultsThe CMBB group had fewer episodes of AM, which included allergic rhinitis or conjunctivitis, wheezing, allergic cough, eczema and urticaria, compared to the control group (p = 0.021). The hazard ratio for increased number of episodes of AM was lower in the CMBB group compared to control (HR, 0.64; 95 % CI 0.47–0.89; p = 0.007). There was no difference in the incidence of respiratory infections and diarrheal disease between groups.ConclusionA cow’s milk-based beverage containing DHA, PDX/GOS, and yeast β-glucan, and supplemented with micronutrients, including zinc, vitamin A and iron, when consumed 3 times/day for 28 weeks by healthy 1- to 4-year-old children was associated with fewer episodes of allergic manifestations in the skin and the respiratory tract.Trial registrationregistration number: NCT01431469

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Cow’s milk-based beverage consumption in 1- to 4-year-olds and allergic manifestations: an RCT

Pontes

Ribeiro

et al. 2015

Nutr J

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“…En otro estudio se observó que la suplementación con 250 mg/día de WGP durante 4 semanas redujo significativamente en 28% los síntomas generales de alergia al polen de ambrosia y en 52% su intensidad; sin embargo, no tuvo ningún efecto en los niveles séricos de IgE. Por otra parte, la suplementación con WGP mejoró en 19% el estado físico general de los sujetos y en un 7% su bienestar emocional, en comparación con el grupo control (57). La actividad anti-alérgica de los β-glucanos también ha sido evaluada en estudios clínicos epidemiológicos y en estudios in vitro (58).…”

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ß-glucanos: ¿qué tipos existen y cuáles son sus beneficios en la salud?

2014

Rev. chil. nutr.

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INTRODUCCIÓNLa importancia de la fibra dietética como parte de una dieta equilibrada para la salud del ser humano está ampliamente reconocida. Los β-glucanos son un tipo de fibra soluble para los cuales se han propuesto efectos sobre la glicemia, los niveles de insulinemia, el colesterol y la inmunidad. Cereales como la cebada y la avena son reconocidos como buenas fuentes de β-glucanos pero también se pueden encontrar en algas y hongos. Asimismo, sus propiedades parecen estar relacionadas con su peso molecular, estructura química y características reológicas, las cuales pueden variar según el origen del β-glucano (1).Debido a sus efectos potenciales sobre la salud, la industria de alimentos ha utilizado cada vez más los β-glucanos para el desarrollo de alimentos funcionales. Además, sus propiedades reológicas han estimulado su incorporación a distintas matrices alimentarias con el objetivo de mejorar la estabilidad, textura y vida útil del alimento, en remplazo de ciertos aditivos o agentes texturizantes artificiales (2).En los cereales, los β-glucanos se encuentran concentradas en las paredes celulares del endospermo, cuyo desarrollo es dependiente de las condiciones geoclimáticas; estas, por lo tanto, inciden en el contenido de β-glucano del cereal. Este es regulado por la enzima β-glucano endohidrolasa (1→3, 1→4), también conocida como licheninasa o 1→3, 1→4 β-glucanasa, cuya función es promover la degradación de la pared celular

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“…Moreover, positive effects of immunomodulation by food have already been described in humans [4]. Specifically, Talbott [5] and Yamada [6] documented positive effects of supplementation of β-glucans on symptoms of pollen allergy. Results of the above studies demonstrate the antiallergic and anti-inflammatory properties of fungal immunomodulators and give hope for the future that they could be increasingly used in the treatment and prevention of atopy in larger populations.…”

Section: Immunomodulation In Atopic Diseasementioning

confidence: 96%

Andosan?-An Anti-Allergic and Anti-Inflammatory Ingredient Prepared from Agaricus blazei Mushroom

Hetl

Therkelsen²,

Nentvich³

et al. 2015

J Clin Cell Immunol

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Andosan™ is an extract prepared from medicinal Basidiomycetes mushrooms, mainly Agaricus blazei Murill (AbM) (82%), but it also contains Hericeum erinaceus (He) (15%) and Grifola frondosa (Gf) (3%), all of which have immunomodulating properties. Whereas He and Gf have been used in traditional Chinese and Japanese medicine against cancer, AbM originates from Brazilian rain forest and was used locally and later abroad as health food for the prevention of a range of diseases, including chronic hepatitis, diabetes and cancer. The mushrooms' health effects are probably due to their content of β-glucans and other smaller immunomodulating polysaccharides and proteoglucans. These effects are mediated through their stimulation of innate immune cells, such as monocytes, NK cells and dendritic cells, and the amelioration of a skewded Th1/Th2 balance and of inflammation. Here, we give an overview of the anti-allergic effects of Andosan™ in a mouse model for allergy and anti-inflammatory effects both in vitro, in healthy individuals and in patients with inflammatory bowel diseases.

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β‐Glucan supplementation, allergy symptoms, and quality of life in self‐described ragweed allergy sufferers

Cited by 25 publications

References 94 publications

Cow’s milk-based beverage consumption in 1- to 4-year-olds and allergic manifestations: an RCT

Cow’s milk-based beverage consumption in 1- to 4-year-olds and allergic manifestations: an RCT

ß-glucanos: ¿qué tipos existen y cuáles son sus beneficios en la salud?

Andosan?-An Anti-Allergic and Anti-Inflammatory Ingredient Prepared from Agaricus blazei Mushroom

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