Ideal Cardiovascular Health Metrics and Risk of Non-Communicable Diseases and Mortality: Dose-Response Meta-Analysis and Systematic Review

Liu, Sibo; Chen, Liangkai; Liu, Xiaohui; Cai, Jian; Ma, Yibin; Wang, Xinyu; Liang, Cai; Li, Chang; Liu, Likun; Yang, Xin; You, Yingqian; Zhang, Yi; Shan, Zhilei; Liu, Liegang

doi:10.2139/ssrn.4010866

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2023

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“…In a recent meta-analysis, Liu et al [9] found no significant association between LS7 as a continuous variable and AF in a pooled analysis of 3 cohort studies with a total of 3,700 incident cases of AF (HR 0.94 [95% CI: 0.86e1.01]; I 2 Z 97.7%), although the individual studies reported a small but significant decrease in the risk of AF. There was substantial heterogeneity between these studies and differences may be related to diverse reasons.…”

Section: Discussionmentioning

confidence: 97%

“…As far as we know, only 3 American population cohorts have shown an inverse association between adherence to LS7 index and the risk of AF [6e8]. However, the magnitude of the effect was small and moreover, the confidence intervals included the null value (pooled HR 0.94 [95% CI: 0.86e1.01]) when the LS7 score was analyzed as a continuous variable in a recent meta-analysis pooling these 3 studies [9].…”

Section: Introductionmentioning

confidence: 99%

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