Objective: To analyze how social innovation actions and practices presented in case studies, generate social impact. Methodology: The meta-synthesis was adopted, which, by identifying empirical research (case studies) and establishing comparative analyses, revealed new possibilities for investigation, deepening and theoretical expansion. Results: The results show the heterogeneity of the concept and actions of social innovation, identify its promoters, driving and/or enabling elements, actor networks, and forms of social impact, and link social innovation and impact to other approaches and opportunities for innovation. Theoretical/Methodological contributions: The study was able to synthesize preponderant elements to reach social impact from social innovation actions, themes little explored in an integrated way. In addition, it explored the meta-synthesis method, reinforcing the application of this research strategy as a tool for building theories and identifying findings that surpass the original conclusions of primary case studies. Originality: Given the differences in social impact detection and measurement, and the lack of a standard for social impact generation through social innovation, this study summarizes empirical findings, categorizes, and identifies aspects and elements that condition social impact generation through social innovation. Social / Management Contributions: In addition to portraying conceptual aspects, drivers and forms of social impact, this study offers a discussion on the integration between driving agents, boosters and networks of actors that can help practitioners of social innovation, public and social managers in stimulating and generation positive results (social impact) from this innovation.