2023
DOI: 10.1186/s12864-023-09296-3
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Identification and characterisation of de novo germline structural variants in two commercial pig lines using trio-based whole genome sequencing

Abstract: Background De novo mutations arising in the germline are a source of genetic variation and their discovery broadens our understanding of genetic disorders and evolutionary patterns. Although the number of de novo single nucleotide variants (dnSNVs) has been studied in a number of species, relatively little is known about the occurrence of de novo structural variants (dnSVs). In this study, we investigated 37 deeply sequenced pig trios from two commercial lines to identify dnSVs present in the o… Show more

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