2008
DOI: 10.1096/fasebj.22.1_supplement.959.10
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Identification and characterization of a novel Muscle Lamin A/C (LMNA) Interacting Protein (MLIP): A regulator of Pax7

Abstract: Specific missense mutations LMNA have been identified to be associated with muscular dystrophy suggesting that LMNA interacts with a muscle specific factor(s). A yeast two‐hybrid screen with LMNA as bait was employed to identify muscle specific proteins. A previously uncharacterized cDNA clone was identified that interacts with LMNA in muscle, MLIP. Preliminary results show MLIP protein is primarily expressed in brain, heart and skeletal muscle. No structural or functional domains have been identified within M… Show more

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