2016
DOI: 10.1016/j.bmcl.2015.11.057
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Identification of a novel class of quinoline–oxadiazole hybrids as anti-tuberculosis agents

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Cited by 42 publications
(22 citation statements)
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“…For instance, the famous anti‐malaria drug quinine is exacted from the congeneric plants firstly. Neither natural quinoline derivatives nor synthetic quinoline derivatives always displayed diversity activities, such as antioxidant activity , antitubercular agents , trypanocidal activities , anticancer , antibacterial activity , aromatase inhibitors , and multi‐trypanosomatid activity . So the synthesis of novel quinoline derivatives has been attracted by many organic chemists.…”
Section: Introductionmentioning
confidence: 99%
“…For instance, the famous anti‐malaria drug quinine is exacted from the congeneric plants firstly. Neither natural quinoline derivatives nor synthetic quinoline derivatives always displayed diversity activities, such as antioxidant activity , antitubercular agents , trypanocidal activities , anticancer , antibacterial activity , aromatase inhibitors , and multi‐trypanosomatid activity . So the synthesis of novel quinoline derivatives has been attracted by many organic chemists.…”
Section: Introductionmentioning
confidence: 99%
“…In modern synthetic chemistry, quinoline compounds have been applied in many fields, such as coordination chemistry, organometallic chemistry, asymmetric synthesis, medicinal chemistry, pesticide chemistry, and materials chemistry. Quinoline is one of the most common chemical skeletons of synthesis chemistry and has been used to discover a number of important bioactive compounds, such as anti‐tubercular agents, anti‐cancer drugs, antioxidants, aromatase inhibitors, multi‐trypanosomatids, trypanocidals, antibacterial agents, etc. Therefore, the synthesis of new quinolone derivatives has attracted many organic chemists.…”
Section: Introductionmentioning
confidence: 99%
“…Bicyclic nitrogen heterocycles are known to possess anti‐mycobacterial potential . The pyrido[2,3‐ d ]pyrimidine scaffold, alternatively known as 5‐deazapteridine, is biologically significant .…”
Section: Introductionmentioning
confidence: 99%