Identification of a novel phenolic compound in litchi (Litchi chinensis Sonn.) pericarp and bioactivity evaluation

Jiang, Guoxiang; Lin, Sen; Wen, Li; Jiang, Yueming; Zhao, Ming; Chen, Feng; Prasad, K. Nagendra; Duan, Xuewu; Yang, Bao

doi:10.1016/j.foodchem.2012.08.089

Cited by 98 publications

(55 citation statements)

References 22 publications

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“…[1]- [3]. The chemical components comprise volatile categories, organic acids and fatty acids, amino acids, saponins, flavonoids, and sugar, and they function significantly on antineoplastic.…”

Section: Introductionmentioning

confidence: 99%

Research Progress on the Antineoplastic Pharmacological Effects and Mechanisms of Litchi Seeds

Zhang¹,

Zhang²

2015

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Researchers have proven the Litchi seeds of possessing salutary pharmacodynamic effects, such as dispelling cold, relieving pain, promoting the circulation of qi, and removing stasis. This has resulted in its categorization as an affinal drug and diet in the traditional Chinese medicine. Important research progress has been obtained on the chemical components, traditional pharmacological effects, antivirus and antitumor effects, their molecular mechanisms and immune effects of litchi seeds in recent years. In this review, we have focused on the antitumor-related effects and mechanisms for the purpose of better utilization and comprehensive understanding of litchi seeds.

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Section: Introductionmentioning

confidence: 99%

Research Progress on the Antineoplastic Pharmacological Effects and Mechanisms of Litchi Seeds

Zhang¹,

Zhang²

2015

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“…is a subtropical non-climacteric fruit from China, which has been widely spread as an economic culture in subtropical areas of many countries (Jiang et al 2013), including Brazil. It is much appreciated by consumers around the world due to its attractive appearance, pleasant taste and nutritional value (Queiroz et al 2015).…”

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confidence: 99%

“…In folk medicine and pharmacological studies, anticancer, anti-inflammatory, antifungal, antiviral, antioxidant, anticoagulant, antidiabetic, antihyperlipidemic, antihyperglycemic, hepato-and cardioprotective activities have been assigned to lychee, its by-products and secondary metabolites (Bhoopat et al 2011, Xu et al 2011, Jiang et al 2013, Huang et al 2014. The pharmacological properties of lychee peel and seed are assigned to the presence of phytochemicals, such as ascorbic acid and phenolic compounds, including gallic acid, flavonoids (procyanidin B4, procyanidin B2 and epicatechin) and anthocyanins (cyanidin-3-rutinoside, cyanidin 3-glucoside, quercetin-3-rutinoside and quercetin-3-glucoside) (Bhoopat et al 2011, Xu et al 2011, Jiang et al 2013.…”

mentioning

confidence: 99%

“…The pharmacological properties of lychee peel and seed are assigned to the presence of phytochemicals, such as ascorbic acid and phenolic compounds, including gallic acid, flavonoids (procyanidin B4, procyanidin B2 and epicatechin) and anthocyanins (cyanidin-3-rutinoside, cyanidin 3-glucoside, quercetin-3-rutinoside and quercetin-3-glucoside) (Bhoopat et al 2011, Xu et al 2011, Jiang et al 2013. Research reported the presence of proanthocyanidins, flavonoids, steroids and sesquiterpenes in lychee seeds (Xu et al 2011), which could be used as a natural antioxidant source, functional ingredient or natural preservative (Prasad et al 2009).…”

mentioning

confidence: 99%

“…Research reported the presence of proanthocyanidins, flavonoids, steroids and sesquiterpenes in lychee seeds (Xu et al 2011), which could be used as a natural antioxidant source, functional ingredient or natural preservative (Prasad et al 2009). The peel contains large amounts of flavonoids and polyphenols (Jiang et al 2013), with a high antioxidant activity (Queiroz et al 2015), responsible for its pharmacological effects (Jiang et al 2013). Even with losses in antioxidant activity due to drying, dried lychee peels have a strong antioxidant activity compared to the fresh fruit, which allows their use as flour (Queiroz et al 2015).…”

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confidence: 99%

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Lychee (Litchi chinensis Sonn.) peel flour: effects on hepatoprotection and dyslipidemia induced by a hypercholesterolemic diet

Queiroz

Abreu

Rocha

et al. 2017

An. Acad. Bras. Ciênc.

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Dyslipidemias are associated with the incidence of cardiovascular diseases, obesity, diabetes, hypertension and hepatic steatosis, being the cause of morbidity and mortality. This study investigated the effects of lychee peel flour (PF) on serum levels of total cholesterol (TC), low-density lipoprotein (LDL-c), triacylglycerols (TAG) and various parameters related to obesity, in rats fed a hypercholesterolemic diet. Therefore, 20 male rats were used. In the first 21 days, the animals were fed a hypercholesterolemic diet, except for control group. In the following 21 days, their diets were modified, and they received a standard diet (Control); hypercholesterolemic (Hyper); hypercholesterolemic + 5% PF (PF5) and hypercholesterolemic + 10% PF (PF10). The results revealed that PF intake attenuated weight gain, reduced body mass index, glucose and the levels of TAG, TC, LDL-c, hepatic enzymes and leptin, besides the percentage of hepatic lipids, liver lipid peroxidation and frequency of severe steatosis. Histological studies of the aorta did not show the formation of the atheromatous plaque. These results reinforce its potential to reduce the risk of diseases associated with obesity.

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Plant Bioresources and their Nutrigenomic Implications on Health

Ismail

Imam

2014

Novel Plant Bioresources

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Identification of a novel phenolic compound in litchi (Litchi chinensis Sonn.) pericarp and bioactivity evaluation

Cited by 98 publications

References 22 publications

Research Progress on the Antineoplastic Pharmacological Effects and Mechanisms of Litchi Seeds

Research Progress on the Antineoplastic Pharmacological Effects and Mechanisms of Litchi Seeds

Lychee (Litchi chinensis Sonn.) peel flour: effects on hepatoprotection and dyslipidemia induced by a hypercholesterolemic diet

Plant Bioresources and their Nutrigenomic Implications on Health

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