Identification of a novel virus in pigs—Bungowannah virus: A possible new species of pestivirus

Kirkland, Peter D.; Frost, Melinda; Finlaison, Deborah S.; King, Katherine R.; Ridpath, Julia F.; Gu, Xingnian

doi:10.1016/j.virusres.2007.05.002

Cited by 141 publications

(142 citation statements)

References 15 publications

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“…The Pronghorn virus was isolated from an apparently blind free ranging pronghorn antelope in the US state of Wyoming (Vilcek et al 2010). The Bungowannah virus was detected on a pig farm in Australia during an outbreak which resulted in numerous sudden deaths, stillbirths and mummified piglets in 2003 (Kirkland et al 2007). …”

Section: Classification Of Pestivirusesmentioning

confidence: 99%

“…Categorization of viruses into new Pestivirus species is determined by a number of factors including; nucleotide sequence comparison, the identification of an N pro coding region, antigenic characterisation and in some cases the host of origin (Kirkland et al 2007;Liu et al 2009). Although the putative Pestiviruses described above have been proposed as new species, to-date four officially recognised species occupy the genus.…”

Section: Classification Of Pestivirusesmentioning

confidence: 99%

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Genetic typing of bovine viral diarrhoea virus in cattle on Irish farms

O’Brien

Garvey

Walsh

et al. 2017

Research in Veterinary Science

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The genotype and subgenotype was established for 325 field viruses and one commercial vaccine viral strain based on the analysis of at least one genomic region. BVDV-1a was the prominent subgenotype (n=317) with BVDV-1b (n=6), BVDV-1d (n=1) and BVDV-1e (n=1) also observed. A number of nucleotide sequence alignments and phylogenetic trees were constructed to represent the relationship between Irish field viruses and reference strains representative of all known BVDV genotypes and subgenotypes. Evidence of both herd specific clustering and circulation of multiple strains within herds was observed; however no evidence of county specific clustering was observed. A number of completely conserved nucleotide regions were observed and the 5'UTR was found to be more conserved than the N pro fragment analysed. The results of this study provide a detailed and comprehensive insight into the genetic diversity of BVDV in circulation within Irish cattle herds and will act as a baseline reference for future BVDV genotyping studies.

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Section: Classification Of Pestivirusesmentioning

confidence: 99%

Section: Classification Of Pestivirusesmentioning

confidence: 99%

Genetic typing of bovine viral diarrhoea virus in cattle on Irish farms

O’Brien

Garvey

Walsh

et al. 2017

Research in Veterinary Science

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“…Two decades ago, a version of this strategy, called sequence-independent single-primer amplification (SISPA) , was shown in combination with immunoscreening to retrieve and aid in the genetic characterization of a Norwalk virus in fecal samples (Matsui et al 1991). This strategy and modifications to it, such as DNase-SISPA (Allander et al 2001) and VIDISCA (van der Hoek et al 2004), have successfully been used to identify a number of viruses, such as new Anello-and Parvoviruses in humans (Jones et al 2005) and Bungowannah virus in pigs with porcine myocarditis (PMC) syndrome (Kirkland et al 2007). …”

Section: Sequence-independent Single-primer Amplificationmentioning

confidence: 99%

Viral metagenomics as an emerging and powerful tool in veterinary medicine

Blomström

2011

Veterinary Quarterly

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New diseases continue to emerge in both human and animal populations, and the importance of animals, as reservoirs for viruses that can cause zoonoses are evident. Thus, an increased knowledge of the viral flora in animals, both in healthy and diseased individuals, is important both for animal and human health. Viral metagenomics is a culture-independent approach that is used to investigate the complete viral genetic populations of a sample. This review describes and discusses the different possible steps of a viral metagenomic study utilizing sequence-independent amplification, high-throughput sequencing, and bioinformatics to identify viruses. With this technology, multiple viruses can be detected simultaneously and novel and highly divergent viruses can be discovered and genetically characterized for the first time. This review also briefly discusses the applications of viral metagenomics in veterinary science and lists some of the viruses discovered within this field.

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“…Pestivirus strains showing unexpected genomic sequences such as M a n u s c r i p t 9 Giraffe (Plowright, 1969), Wisent Casimir (Becher et al, 1999), Chamois-1 (Arnal et al, 2004), Pronghorn (Vilček et al, 2005), HoBi group strains (Schirrmeier et al, 2004;Cortez et al, 2006;Liu et al, 2009a) and Bungowannah (Kirkland et al, 2007) have been characterized easily and clustered within the genus by PNS method. The procedures require constant adaptability to eventual new and different observations.…”

Section: Page 8 Of 18mentioning

confidence: 99%

“…The relatively large number of new deposited sequences of isolates from domestic and wild animals and the recent evidence of novel "atypical" Pestivirus sequences, as for example the strains D32/00_'HoBi' (Schirrmeier et al, 2004) and Th/04_KhonKaen (Liu et al, 2009a) isolated in cattle infected naturally, in Brazil and Thailand, respectively, or the Bungowannah virus isolated from piglets in Australia (Kirkland et al, 2007), motivated the necessity for a updated application of the PNS method.…”

mentioning

confidence: 99%